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RNA with chemotherapeutic base analogues as a dual-functional anti-cancer drug.
Jarzebska NT, Tusup M, Frei J, Weiss T, Holzinger T, Mellett M, Diken M, Bredl S, Weller M, Speck RF, Kündig TM, Sahin U, Pascolo S. Jarzebska NT, et al. Among authors: diken m. Oncoimmunology. 2022 Nov 18;11(1):2147665. doi: 10.1080/2162402X.2022.2147665. eCollection 2022. Oncoimmunology. 2022. PMID: 36419823 Free PMC article.
Dextran-based therapeutic nanoparticles for hepatic drug delivery.
Foerster F, Bamberger D, Schupp J, Weilbächer M, Kaps L, Strobl S, Radi L, Diken M, Strand D, Tuettenberg A, Wich PR, Schuppan D. Foerster F, et al. Among authors: diken m. Nanomedicine (Lond). 2016 Oct;11(20):2663-2677. doi: 10.2217/nnm-2016-0156. Epub 2016 Sep 15. Nanomedicine (Lond). 2016. PMID: 27628057
Vaccination with trifunctional nanoparticles that address CD8+ dendritic cells inhibits growth of established melanoma.
Shen L, Krauthäuser S, Fischer K, Hobernik D, Abassi Y, Dzionek A, Nikolaev A, Voltz N, Diken M, Krummen M, Montermann E, Tubbe I, Lorenz S, Strand D, Schild H, Grabbe S, Bros M. Shen L, et al. Among authors: diken m. Nanomedicine (Lond). 2016 Oct;11(20):2647-2662. doi: 10.2217/nnm-2016-0174. Epub 2016 Sep 15. Nanomedicine (Lond). 2016. PMID: 27628310
An RNA vaccine drives immunity in checkpoint-inhibitor-treated melanoma.
Sahin U, Oehm P, Derhovanessian E, Jabulowsky RA, Vormehr M, Gold M, Maurus D, Schwarck-Kokarakis D, Kuhn AN, Omokoko T, Kranz LM, Diken M, Kreiter S, Haas H, Attig S, Rae R, Cuk K, Kemmer-Brück A, Breitkreuz A, Tolliver C, Caspar J, Quinkhardt J, Hebich L, Stein M, Hohberger A, Vogler I, Liebig I, Renken S, Sikorski J, Leierer M, Müller V, Mitzel-Rink H, Miederer M, Huber C, Grabbe S, Utikal J, Pinter A, Kaufmann R, Hassel JC, Loquai C, Türeci Ö. Sahin U, et al. Among authors: diken m. Nature. 2020 Sep;585(7823):107-112. doi: 10.1038/s41586-020-2537-9. Epub 2020 Jul 29. Nature. 2020. PMID: 32728218 Clinical Trial.
91 results