Wright GD - Search Results

1

Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae.

Falconer SB, Reid-Yu SA, King AM, Gehrke SS, Wang W, Britten JF, Coombes BK, Wright GD, Brown ED. Falconer SB, et al. Among authors: wright gd. ACS Infect Dis. 2015 Nov 13;1(11):533-43. doi: 10.1021/acsinfecdis.5b00033. Epub 2015 May 26. ACS Infect Dis. 2015. PMID: 27623408

2

Multicopy suppressors for novel antibacterial compounds reveal targets and drug efflux susceptibility.

Li X, Zolli-Juran M, Cechetto JD, Daigle DM, Wright GD, Brown ED. Li X, et al. Among authors: wright gd. Chem Biol. 2004 Oct;11(10):1423-30. doi: 10.1016/j.chembiol.2004.08.014. Chem Biol. 2004. PMID: 15489169

3

New targets and screening approaches in antimicrobial drug discovery.

Brown ED, Wright GD. Brown ED, et al. Among authors: wright gd. Chem Rev. 2005 Feb;105(2):759-74. doi: 10.1021/cr030116o. Chem Rev. 2005. PMID: 15700964 Review. No abstract available.

4

Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function.

Ejim LJ, Blanchard JE, Koteva KP, Sumerfield R, Elowe NH, Chechetto JD, Brown ED, Junop MS, Wright GD. Ejim LJ, et al. Among authors: wright gd. J Med Chem. 2007 Feb 22;50(4):755-64. doi: 10.1021/jm061132r. J Med Chem. 2007. PMID: 17300162

5

The wall teichoic acid polymerase TagF efficiently synthesizes poly(glycerol phosphate) on the TagB product lipid III.

Pereira MP, Schertzer JW, D'Elia MA, Koteva KP, Hughes DW, Wright GD, Brown ED. Pereira MP, et al. Among authors: wright gd. Chembiochem. 2008 Jun 16;9(9):1385-90. doi: 10.1002/cbic.200800026. Chembiochem. 2008. PMID: 18465758 No abstract available.

6

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy.

Ejim L, Farha MA, Falconer SB, Wildenhain J, Coombes BK, Tyers M, Brown ED, Wright GD. Ejim L, et al. Among authors: wright gd. Nat Chem Biol. 2011 Jun;7(6):348-50. doi: 10.1038/nchembio.559. Epub 2011 Apr 24. Nat Chem Biol. 2011. PMID: 21516114

7

Inhibition of WTA synthesis blocks the cooperative action of PBPs and sensitizes MRSA to β-lactams.

Farha MA, Leung A, Sewell EW, D'Elia MA, Allison SE, Ejim L, Pereira PM, Pinho MG, Wright GD, Brown ED. Farha MA, et al. Among authors: wright gd. ACS Chem Biol. 2013 Jan 18;8(1):226-33. doi: 10.1021/cb300413m. Epub 2012 Oct 19. ACS Chem Biol. 2013. PMID: 23062620 Free PMC article.

8

The comprehensive antibiotic resistance database.

McArthur AG, Waglechner N, Nizam F, Yan A, Azad MA, Baylay AJ, Bhullar K, Canova MJ, De Pascale G, Ejim L, Kalan L, King AM, Koteva K, Morar M, Mulvey MR, O'Brien JS, Pawlowski AC, Piddock LJ, Spanogiannopoulos P, Sutherland AD, Tang I, Taylor PL, Thaker M, Wang W, Yan M, Yu T, Wright GD. McArthur AG, et al. Among authors: wright gd. Antimicrob Agents Chemother. 2013 Jul;57(7):3348-57. doi: 10.1128/AAC.00419-13. Epub 2013 May 6. Antimicrob Agents Chemother. 2013. PMID: 23650175 Free PMC article.

9

Identifying producers of antibacterial compounds by screening for antibiotic resistance.

Thaker MN, Wang W, Spanogiannopoulos P, Waglechner N, King AM, Medina R, Wright GD. Thaker MN, et al. Among authors: wright gd. Nat Biotechnol. 2013 Oct;31(10):922-7. doi: 10.1038/nbt.2685. Epub 2013 Sep 22. Nat Biotechnol. 2013. PMID: 24056948

10

Antibiotic resistance-the need for global solutions.

Laxminarayan R, Duse A, Wattal C, Zaidi AK, Wertheim HF, Sumpradit N, Vlieghe E, Hara GL, Gould IM, Goossens H, Greko C, So AD, Bigdeli M, Tomson G, Woodhouse W, Ombaka E, Peralta AQ, Qamar FN, Mir F, Kariuki S, Bhutta ZA, Coates A, Bergstrom R, Wright GD, Brown ED, Cars O. Laxminarayan R, et al. Among authors: wright gd. Lancet Infect Dis. 2013 Dec;13(12):1057-98. doi: 10.1016/S1473-3099(13)70318-9. Epub 2013 Nov 17. Lancet Infect Dis. 2013. PMID: 24252483

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