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Plazomicin is effective in a non-human primate pneumonic plague model.
Bioorg Med Chem. 2016 Dec 15;24(24):6429-6439. doi: 10.1016/j.bmc.2016.08.049. Epub 2016 Aug 27.
Bioorg Med Chem. 2016.
PMID: 27614915
Free article.
Protection in mice passively immunized with serum from cynomolgus macaques and humans vaccinated with recombinant plague vaccine (rF1V).
Fellows P, Adamovicz J, Hartings J, Sherwood R, Mega W, Brasel T, Barr E, Holland L, Lin W, Rom A, Blackwelder W, Price J, Morris S, Snow D, Hart MK.
Fellows P, et al.
Vaccine. 2010 Nov 16;28(49):7748-56. doi: 10.1016/j.vaccine.2010.09.062. Epub 2010 Oct 15.
Vaccine. 2010.
PMID: 20920572
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Levofloxacin cures experimental pneumonic plague in African green monkeys.
Layton RC, Mega W, McDonald JD, Brasel TL, Barr EB, Gigliotti AP, Koster F.
Layton RC, et al.
PLoS Negl Trop Dis. 2011 Feb 8;5(2):e959. doi: 10.1371/journal.pntd.0000959.
PLoS Negl Trop Dis. 2011.
PMID: 21347450
Free PMC article.
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Gepotidacin is efficacious in a nonhuman primate model of pneumonic plague.
Jakielaszek C, Hossain M, Qian L, Fishman C, Widdowson K, Hilliard JJ, Mannino F, Raychaudhuri A, Carniel E, Demons S, Heine HS, Hershfield J, Russo R, Mega WM, Revelli D, O'Dwyer K.
Jakielaszek C, et al. Among authors: mega wm.
Sci Transl Med. 2022 Jun;14(647):eabg1787. doi: 10.1126/scitranslmed.abg1787. Epub 2022 Jun 1.
Sci Transl Med. 2022.
PMID: 35648812
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A chimeric Sindbis-based vaccine protects cynomolgus macaques against a lethal aerosol challenge of eastern equine encephalitis virus.
Roy CJ, Adams AP, Wang E, Leal G, Seymour RL, Sivasubramani SK, Mega W, Frolov I, Didier PJ, Weaver SC.
Roy CJ, et al.
Vaccine. 2013 Mar 1;31(11):1464-70. doi: 10.1016/j.vaccine.2013.01.014. Epub 2013 Jan 16.
Vaccine. 2013.
PMID: 23333212
Free PMC article.
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Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection.
Reed MD, Wilder JA, Mega WM, Hutt JA, Kuehl PJ, Valderas MW, Chew LL, Liang BC, Squires CH.
Reed MD, et al. Among authors: mega wm.
PLoS One. 2015 Jul 24;10(7):e0130952. doi: 10.1371/journal.pone.0130952. eCollection 2015.
PLoS One. 2015.
PMID: 26207820
Free PMC article.
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Integrative "omic" analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response syndromes.
Langley RJ, Tipper JL, Bruse S, Baron RM, Tsalik EL, Huntley J, Rogers AJ, Jaramillo RJ, O'Donnell D, Mega WM, Keaton M, Kensicki E, Gazourian L, Fredenburgh LE, Massaro AF, Otero RM, Fowler VG Jr, Rivers EP, Woods CW, Kingsmore SF, Sopori ML, Perrella MA, Choi AM, Harrod KS.
Langley RJ, et al. Among authors: mega wm.
Am J Respir Crit Care Med. 2014 Aug 15;190(4):445-55. doi: 10.1164/rccm.201404-0624OC.
Am J Respir Crit Care Med. 2014.
PMID: 25054455
Free PMC article.
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