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Plazomicin is effective in a non-human primate pneumonic plague model.
Mega WM, Doyle-Eisele M, Cass RT, Kostrub CF, Sherwood RL, Metz MA, Cirz RT. Mega WM, et al. Among authors: cass rt. Bioorg Med Chem. 2016 Dec 15;24(24):6429-6439. doi: 10.1016/j.bmc.2016.08.049. Epub 2016 Aug 27. Bioorg Med Chem. 2016. PMID: 27614915 Free article.
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton's Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies.
Robbins DW, Noviski MA, Tan YS, Konst ZA, Kelly A, Auger P, Brathaban N, Cass R, Chan ML, Cherala G, Clifton MC, Gajewski S, Ingallinera TG, Karr D, Kato D, Ma J, McKinnell J, McIntosh J, Mihalic J, Murphy B, Panga JR, Peng G, Powers J, Perez L, Rountree R, Tenn-McClellan A, Sands AT, Weiss DR, Wu J, Ye J, Guiducci C, Hansen G, Cohen F. Robbins DW, et al. J Med Chem. 2024 Feb 22;67(4):2321-2336. doi: 10.1021/acs.jmedchem.3c01007. Epub 2024 Feb 1. J Med Chem. 2024. PMID: 38300987
Telavancin, a multifunctional lipoglycopeptide, disrupts both cell wall synthesis and cell membrane integrity in methicillin-resistant Staphylococcus aureus.
Higgins DL, Chang R, Debabov DV, Leung J, Wu T, Krause KM, Sandvik E, Hubbard JM, Kaniga K, Schmidt DE Jr, Gao Q, Cass RT, Karr DE, Benton BM, Humphrey PP. Higgins DL, et al. Among authors: cass rt. Antimicrob Agents Chemother. 2005 Mar;49(3):1127-34. doi: 10.1128/AAC.49.3.1127-1134.2005. Antimicrob Agents Chemother. 2005. PMID: 15728913 Free PMC article.
16 results