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Acute graft-versus-host disease is regulated by an IL-17-sensitive microbiome.
Varelias A, Ormerod KL, Bunting MD, Koyama M, Gartlan KH, Kuns RD, Lachner N, Locke KR, Lim CY, Henden AS, Zhang P, Clouston AD, Hasnain SZ, McGuckin MA, Blazar BR, MacDonald KP, Hugenholtz P, Hill GR. Varelias A, et al. Among authors: lachner n. Blood. 2017 Apr 13;129(15):2172-2185. doi: 10.1182/blood-2016-08-732628. Epub 2017 Jan 30. Blood. 2017. PMID: 28137828 Free PMC article.
Recipient mucosal-associated invariant T cells control GVHD within the colon.
Varelias A, Bunting MD, Ormerod KL, Koyama M, Olver SD, Straube J, Kuns RD, Robb RJ, Henden AS, Cooper L, Lachner N, Gartlan KH, Lantz O, Kjer-Nielsen L, Mak JY, Fairlie DP, Clouston AD, McCluskey J, Rossjohn J, Lane SW, Hugenholtz P, Hill GR. Varelias A, et al. Among authors: lachner n. J Clin Invest. 2018 May 1;128(5):1919-1936. doi: 10.1172/JCI91646. Epub 2018 Apr 9. J Clin Invest. 2018. PMID: 29629900 Free PMC article.
14 results