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Mutational signatures in esophageal adenocarcinoma define etiologically distinct subgroups with therapeutic relevance.
Secrier M, Li X, de Silva N, Eldridge MD, Contino G, Bornschein J, MacRae S, Grehan N, O'Donovan M, Miremadi A, Yang TP, Bower L, Chettouh H, Crawte J, Galeano-Dalmau N, Grabowska A, Saunders J, Underwood T, Waddell N, Barbour AP, Nutzinger B, Achilleos A, Edwards PA, Lynch AG, Tavaré S, Fitzgerald RC; Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium. Secrier M, et al. Among authors: tavare s. Nat Genet. 2016 Oct;48(10):1131-41. doi: 10.1038/ng.3659. Epub 2016 Sep 5. Nat Genet. 2016. PMID: 27595477 Free PMC article.
beadarray: R classes and methods for Illumina bead-based data.
Dunning MJ, Smith ML, Ritchie ME, Tavaré S. Dunning MJ, et al. Among authors: tavare s. Bioinformatics. 2007 Aug 15;23(16):2183-4. doi: 10.1093/bioinformatics/btm311. Epub 2007 Jun 22. Bioinformatics. 2007. PMID: 17586828
Statistical issues in the analysis of Illumina data.
Dunning MJ, Barbosa-Morais NL, Lynch AG, Tavaré S, Ritchie ME. Dunning MJ, et al. Among authors: tavare s. BMC Bioinformatics. 2008 Feb 6;9:85. doi: 10.1186/1471-2105-9-85. BMC Bioinformatics. 2008. PMID: 18254947 Free PMC article.
BayesPeak: Bayesian analysis of ChIP-seq data.
Spyrou C, Stark R, Lynch AG, Tavaré S. Spyrou C, et al. Among authors: tavare s. BMC Bioinformatics. 2009 Sep 21;10:299. doi: 10.1186/1471-2105-10-299. BMC Bioinformatics. 2009. PMID: 19772557 Free PMC article.
The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.
Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S; METABRIC Group; Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L, Ellis I, Purushotham A, Børresen-Dale AL, Brenton JD, Tavaré S, Caldas C, Aparicio S. Curtis C, et al. Among authors: tavare s. Nature. 2012 Apr 18;486(7403):346-52. doi: 10.1038/nature10983. Nature. 2012. PMID: 22522925 Free PMC article.
Phenotype specific analyses reveal distinct regulatory mechanism for chronically activated p53.
Kirschner K, Samarajiwa SA, Cairns JM, Menon S, Pérez-Mancera PA, Tomimatsu K, Bermejo-Rodriguez C, Ito Y, Chandra T, Narita M, Lyons SK, Lynch AG, Kimura H, Ohbayashi T, Tavaré S, Narita M. Kirschner K, et al. Among authors: tavare s. PLoS Genet. 2015 Mar 19;11(3):e1005053. doi: 10.1371/journal.pgen.1005053. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25790137 Free PMC article.
254 results