Regulation of type 1 inositol 1,4,5-trisphosphate-gated calcium channels by InsP3 and calcium: Simulation of single channel kinetics based on ligand binding and electrophysiological analysis.
Moraru II, Kaftan EJ, Ehrlich BE, Watras J.
Moraru II, et al. Among authors: ehrlich be.
J Gen Physiol. 1999 Jun;113(6):837-49. doi: 10.1085/jgp.113.6.837.
J Gen Physiol. 1999.
PMID: 10352034
Free PMC article.
Cytosolic calcium acts as both a coagonist and an inhibitor of the type 1 inositol 1,4,5-trisphosphate (InsP3)-gated Ca channel, resulting in a bell-shaped Ca dependence of channel activity (Bezprozvanny, I., J. Watras, and B.E. Ehrlich. 1991. Nature. 351:751-754; Finch, E …
Cytosolic calcium acts as both a coagonist and an inhibitor of the type 1 inositol 1,4,5-trisphosphate (InsP3)-gated Ca channel, resulting i …