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The administration route is decisive for the ability of the vaccine adjuvant CAF09 to induce antigen-specific CD8(+) T-cell responses: The immunological consequences of the biodistribution profile.
Schmidt ST, Khadke S, Korsholm KS, Perrie Y, Rades T, Andersen P, Foged C, Christensen D. Schmidt ST, et al. Among authors: foged c. J Control Release. 2016 Oct 10;239:107-17. doi: 10.1016/j.jconrel.2016.08.034. Epub 2016 Aug 26. J Control Release. 2016. PMID: 27574990 Free PMC article.
The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes.
Korsholm KS, Agger EM, Foged C, Christensen D, Dietrich J, Andersen CS, Geisler C, Andersen P. Korsholm KS, et al. Among authors: foged c. Immunology. 2007 Jun;121(2):216-26. doi: 10.1111/j.1365-2567.2007.02560.x. Epub 2007 Feb 14. Immunology. 2007. PMID: 17302734 Free PMC article.
alpha,alpha'-trehalose 6,6'-dibehenate in non-phospholipid-based liposomes enables direct interaction with trehalose, offering stability during freeze-drying.
Christensen D, Kirby D, Foged C, Agger EM, Andersen P, Perrie Y, Nielsen HM. Christensen D, et al. Among authors: foged c. Biochim Biophys Acta. 2008 May;1778(5):1365-73. doi: 10.1016/j.bbamem.2008.01.013. Epub 2008 Jan 26. Biochim Biophys Acta. 2008. PMID: 18261458 Free article.
In previous experiments we have shown that trehalose is able to protect a non-phospholipid-based liposomal adjuvant (designated CAF01) composed of the cationic dimethyldioctadecylammonium (DDA) and trehalose 6,6'-dibehenate (TDB) during freeze-drying [D. Christensen, C. …
In previous experiments we have shown that trehalose is able to protect a non-phospholipid-based liposomal adjuvant (designated CAF01) compo …
145 results