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Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses.
Bourgeais J, Ishac N, Medrzycki M, Brachet-Botineau M, Desbourdes L, Gouilleux-Gruart V, Pecnard E, Rouleux-Bonnin F, Gyan E, Domenech J, Mazurier F, Moriggl R, Bunting KD, Herault O, Gouilleux F. Bourgeais J, et al. Among authors: moriggl r. Oncotarget. 2017 Jun 27;8(26):41876-41889. doi: 10.18632/oncotarget.11480. Oncotarget. 2017. PMID: 27566554 Free PMC article.
Stat5 tetramer formation is associated with leukemogenesis.
Moriggl R, Sexl V, Kenner L, Duntsch C, Stangl K, Gingras S, Hoffmeyer A, Bauer A, Piekorz R, Wang D, Bunting KD, Wagner EF, Sonneck K, Valent P, Ihle JN, Beug H. Moriggl R, et al. Cancer Cell. 2005 Jan;7(1):87-99. doi: 10.1016/j.ccr.2004.12.010. Cancer Cell. 2005. PMID: 15652752 Free article.
The different functions of Stat5 and chromatin alteration through Stat5 proteins.
Kornfeld JW, Grebien F, Kerenyi MA, Friedbichler K, Kovacic B, Zankl B, Hoelbl A, Nivarti H, Beug H, Sexl V, Muller M, Kenner L, Mullner EW, Gouilleux F, Moriggl R. Kornfeld JW, et al. Among authors: moriggl r. Front Biosci. 2008 May 1;13:6237-54. doi: 10.2741/3151. Front Biosci. 2008. PMID: 18508657 Free PMC article. Review.
223 results