Langlois X - Search Results

1

Metabotropic glutamate receptor 2/3 density and its relation to the hippocampal neuropathology in a model of temporal lobe epilepsy in rats.

Ali I, Boets S, Janssens P, Van Eetveldt A, Amhaoul H, Langlois X, Dedeurwaerdere S. Ali I, et al. Among authors: langlois x. Epilepsy Res. 2016 Nov;127:55-59. doi: 10.1016/j.eplepsyres.2016.08.010. Epub 2016 Aug 13. Epilepsy Res. 2016. PMID: 27565411

2

Memantine-induced brain activation as a model for the rapid screening of potential novel antipsychotic compounds: exemplified by activity of an mGlu2/3 receptor agonist.

Dedeurwaerdere S, Wintmolders C, Straetemans R, Pemberton D, Langlois X. Dedeurwaerdere S, et al. Among authors: langlois x. Psychopharmacology (Berl). 2011 Mar;214(2):505-14. doi: 10.1007/s00213-010-2052-z. Epub 2010 Oct 31. Psychopharmacology (Berl). 2011. PMID: 21057775

3

Patterns of brain glucose metabolism induced by phosphodiesterase 10A inhibitors in the mouse: a potential translational biomarker.

Dedeurwaerdere S, Wintmolders C, Vanhoof G, Langlois X. Dedeurwaerdere S, et al. Among authors: langlois x. J Pharmacol Exp Ther. 2011 Oct;339(1):210-7. doi: 10.1124/jpet.111.182766. Epub 2011 Jul 8. J Pharmacol Exp Ther. 2011. PMID: 21742809

4

Synthesis, in vivo occupancy, and radiolabeling of potent phosphodiesterase subtype-10 inhibitors as candidates for positron emission tomography imaging.

Andrés JI, De Angelis M, Alcázar J, Iturrino L, Langlois X, Dedeurwaerdere S, Lenaerts I, Vanhoof G, Celen S, Bormans G. Andrés JI, et al. Among authors: langlois x. J Med Chem. 2011 Aug 25;54(16):5820-35. doi: 10.1021/jm200536d. Epub 2011 Aug 2. J Med Chem. 2011. PMID: 21777010

5

The [18F]FDG μPET readout of a brain activation model to evaluate the metabotropic glutamate receptor 2 positive allosteric modulator JNJ-42153605.

Wyckhuys T, Wyffels L, Langlois X, Schmidt M, Stroobants S, Staelens S. Wyckhuys T, et al. Among authors: langlois x. J Pharmacol Exp Ther. 2014 Aug;350(2):375-86. doi: 10.1124/jpet.114.213959. Epub 2014 Jun 4. J Pharmacol Exp Ther. 2014. PMID: 24898267

6

Preclinical evaluation of 18F-JNJ41510417 as a radioligand for PET imaging of phosphodiesterase-10A in the brain.

Celen S, Koole M, De Angelis M, Sannen I, Chitneni SK, Alcazar J, Dedeurwaerdere S, Moechars D, Schmidt M, Verbruggen A, Langlois X, Van Laere K, Andrés JI, Bormans G. Celen S, et al. Among authors: langlois x. J Nucl Med. 2010 Oct;51(10):1584-91. doi: 10.2967/jnumed.110.077040. Epub 2010 Sep 16. J Nucl Med. 2010. PMID: 20847170 Free article.

7

Negative versus positive allosteric modulation of metabotropic glutamate receptors (mGluR5): indices for potential pro-cognitive drug properties based on EEG network oscillations and sleep-wake organization in rats.

Ahnaou A, Langlois X, Steckler T, Bartolome-Nebreda JM, Drinkenburg WH. Ahnaou A, et al. Among authors: langlois x. Psychopharmacology (Berl). 2015 Mar;232(6):1107-22. doi: 10.1007/s00213-014-3746-4. Epub 2014 Oct 18. Psychopharmacology (Berl). 2015. PMID: 25323624

8

Metabotropic glutamate 1 receptor distribution and occupancy in the rat brain: a quantitative autoradiographic study using [3H]R214127.

Lavreysen H, Pereira SN, Leysen JE, Langlois X, Lesage AS. Lavreysen H, et al. Among authors: langlois x. Neuropharmacology. 2004 Apr;46(5):609-19. doi: 10.1016/j.neuropharm.2003.11.014. Neuropharmacology. 2004. PMID: 14996538

9

What We Observe In Vivo Is Not Always What We See In Vitro: Development and Validation of 11C-JNJ-42491293, A Novel Radioligand for mGluR2.

Leurquin-Sterk G, Celen S, Van Laere K, Koole M, Bormans G, Langlois X, Van Hecken A, Te Riele P, Alcázar J, Verbruggen A, de Hoon J, Andrés JI, Schmidt ME. Leurquin-Sterk G, et al. Among authors: langlois x. J Nucl Med. 2017 Jan;58(1):110-116. doi: 10.2967/jnumed.116.176628. Epub 2016 Jul 28. J Nucl Med. 2017. PMID: 27469358 Free article.

10

N-acetylcysteine- and MK-801-induced changes in glutamate levels do not affect in vivo binding of metabotropic glutamate 5 receptor radioligand 11C-ABP688 in rat brain.

Wyckhuys T, Verhaeghe J, Wyffels L, Langlois X, Schmidt M, Stroobants S, Staelens S. Wyckhuys T, et al. Among authors: langlois x. J Nucl Med. 2013 Nov;54(11):1954-61. doi: 10.2967/jnumed.113.121608. Epub 2013 Sep 19. J Nucl Med. 2013. PMID: 24050937 Free article.

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