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An S-warfarin and AZD1981 interaction: in vitro and clinical pilot data suggest the N-deacetylated amino acid metabolite as the primary perpetrator.
Grime K, Pehrson R, Nordell P, Gillen M, Kühn W, Mant T, Brännström M, Svanberg P, Jones B, Brealey C. Grime K, et al. Among authors: gillen m. Br J Clin Pharmacol. 2017 Feb;83(2):381-392. doi: 10.1111/bcp.13102. Epub 2016 Oct 13. Br J Clin Pharmacol. 2017. PMID: 27558866 Free PMC article. Clinical Trial.
Effects of CYP3A4 Inhibitors Ketoconazole and Verapamil and the CYP3A4 Inducer Rifampicin on the Pharmacokinetic Parameters of Fostamatinib: Results from In Vitro and Phase I Clinical Studies.
Martin P, Gillen M, Millson D, Oliver S, Brealey C, Grossbard EB, Baluom M, Lau D, Sweeny D, Mant T, Craven K. Martin P, et al. Among authors: gillen m. Drugs R D. 2016 Mar;16(1):81-92. doi: 10.1007/s40268-015-0118-4. Drugs R D. 2016. PMID: 26739683 Free PMC article. Clinical Trial.
Pharmacokinetics, Pharmacodynamics, and Tolerability of Concomitant Multiple Dose Administration of Verinurad (RDEA3170) and Allopurinol in Adult Male Subjects With Gout.
Kankam M, Hall J, Gillen M, Yang X, Shen Z, Lee C, Liu S, Miner JN, Walker S, Clauson V, Wilson D, Nguyen M. Kankam M, et al. Among authors: gillen m. J Clin Pharmacol. 2018 Sep;58(9):1214-1222. doi: 10.1002/jcph.1119. Epub 2018 May 7. J Clin Pharmacol. 2018. PMID: 29733447 Free PMC article. Clinical Trial.
178 results