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Somatic Genome Editing Goes Viral.
Zafra MP, Dow LE. Zafra MP, et al. Trends Mol Med. 2016 Oct;22(10):831-833. doi: 10.1016/j.molmed.2016.08.004. Epub 2016 Aug 20. Trends Mol Med. 2016. PMID: 27555346 Free PMC article.
Optimized base editors enable efficient editing in cells, organoids and mice.
Zafra MP, Schatoff EM, Katti A, Foronda M, Breinig M, Schweitzer AY, Simon A, Han T, Goswami S, Montgomery E, Thibado J, Kastenhuber ER, Sánchez-Rivera FJ, Shi J, Vakoc CR, Lowe SW, Tschaharganeh DF, Dow LE. Zafra MP, et al. Nat Biotechnol. 2018 Oct;36(9):888-893. doi: 10.1038/nbt.4194. Epub 2018 Jul 3. Nat Biotechnol. 2018. PMID: 29969439 Free PMC article.
Base editing the mammalian genome.
Schatoff EM, Zafra MP, Dow LE. Schatoff EM, et al. Among authors: zafra mp. Methods. 2019 Jul 15;164-165:100-108. doi: 10.1016/j.ymeth.2019.02.022. Epub 2019 Mar 2. Methods. 2019. PMID: 30836137 Free PMC article. Review.
Adenine base editing in an adult mouse model of tyrosinaemia.
Song CQ, Jiang T, Richter M, Rhym LH, Koblan LW, Zafra MP, Schatoff EM, Doman JL, Cao Y, Dow LE, Zhu LJ, Anderson DG, Liu DR, Yin H, Xue W. Song CQ, et al. Among authors: zafra mp. Nat Biomed Eng. 2020 Jan;4(1):125-130. doi: 10.1038/s41551-019-0357-8. Epub 2019 Feb 25. Nat Biomed Eng. 2020. PMID: 31740768 Free PMC article.
In situ CRISPR-Cas9 base editing for the development of genetically engineered mouse models of breast cancer.
Annunziato S, Lutz C, Henneman L, Bhin J, Wong K, Siteur B, van Gerwen B, de Korte-Grimmerink R, Zafra MP, Schatoff EM, Drenth AP, van der Burg E, Eijkman T, Mukherjee S, Boroviak K, Wessels LF, van de Ven M, Huijbers IJ, Adams DJ, Dow LE, Jonkers J. Annunziato S, et al. Among authors: zafra mp. EMBO J. 2020 Mar 2;39(5):e102169. doi: 10.15252/embj.2019102169. Epub 2020 Jan 13. EMBO J. 2020. PMID: 31930530 Free PMC article.
Lineage Reversion Drives WNT Independence in Intestinal Cancer.
Han T, Goswami S, Hu Y, Tang F, Zafra MP, Murphy C, Cao Z, Poirier JT, Khurana E, Elemento O, Hechtman JF, Ganesh K, Yaeger R, Dow LE. Han T, et al. Among authors: zafra mp. Cancer Discov. 2020 Oct;10(10):1590-1609. doi: 10.1158/2159-8290.CD-19-1536. Epub 2020 Jun 16. Cancer Discov. 2020. PMID: 32546576 Free PMC article.
27 results