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Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.
von Schimmelmann M, Feinberg PA, Sullivan JM, Ku SM, Badimon A, Duff MK, Wang Z, Lachmann A, Dewell S, Ma'ayan A, Han MH, Tarakhovsky A, Schaefer A. von Schimmelmann M, et al. Among authors: schaefer a. Nat Neurosci. 2016 Oct;19(10):1321-30. doi: 10.1038/nn.4360. Epub 2016 Aug 15. Nat Neurosci. 2016. PMID: 27526204 Free PMC article.
Essential role of the histone methyltransferase G9a in cocaine-induced plasticity.
Maze I, Covington HE 3rd, Dietz DM, LaPlant Q, Renthal W, Russo SJ, Mechanic M, Mouzon E, Neve RL, Haggarty SJ, Ren Y, Sampath SC, Hurd YL, Greengard P, Tarakhovsky A, Schaefer A, Nestler EJ. Maze I, et al. Among authors: schaefer a. Science. 2010 Jan 8;327(5962):213-6. doi: 10.1126/science.1179438. Science. 2010. PMID: 20056891 Free PMC article.
Epigenetic mechanisms of mental retardation.
Schaefer A, Tarakhovsky A, Greengard P. Schaefer A, et al. Prog Drug Res. 2011;67:125-46. doi: 10.1007/978-3-7643-8989-5_7. Prog Drug Res. 2011. PMID: 21141728 Review.
MicroRNA-128 governs neuronal excitability and motor behavior in mice.
Tan CL, Plotkin JL, Venø MT, von Schimmelmann M, Feinberg P, Mann S, Handler A, Kjems J, Surmeier DJ, O'Carroll D, Greengard P, Schaefer A. Tan CL, et al. Among authors: schaefer a. Science. 2013 Dec 6;342(6163):1254-8. doi: 10.1126/science.1244193. Science. 2013. PMID: 24311694 Free PMC article.
G9a influences neuronal subtype specification in striatum.
Maze I, Chaudhury D, Dietz DM, Von Schimmelmann M, Kennedy PJ, Lobo MK, Daws SE, Miller ML, Bagot RC, Sun H, Turecki G, Neve RL, Hurd YL, Shen L, Han MH, Schaefer A, Nestler EJ. Maze I, et al. Among authors: schaefer a. Nat Neurosci. 2014 Apr;17(4):533-9. doi: 10.1038/nn.3670. Epub 2014 Mar 2. Nat Neurosci. 2014. PMID: 24584053 Free PMC article.
An AUTS2-Polycomb complex activates gene expression in the CNS.
Gao Z, Lee P, Stafford JM, von Schimmelmann M, Schaefer A, Reinberg D. Gao Z, et al. Among authors: schaefer a. Nature. 2014 Dec 18;516(7531):349-54. doi: 10.1038/nature13921. Nature. 2014. PMID: 25519132 Free PMC article.
Autism-like syndrome is induced by pharmacological suppression of BET proteins in young mice.
Sullivan JM, Badimon A, Schaefer U, Ayata P, Gray J, Chung CW, von Schimmelmann M, Zhang F, Garton N, Smithers N, Lewis H, Tarakhovsky A, Prinjha RK, Schaefer A. Sullivan JM, et al. Among authors: schaefer a, schaefer u. J Exp Med. 2015 Oct 19;212(11):1771-81. doi: 10.1084/jem.20151271. Epub 2015 Sep 21. J Exp Med. 2015. PMID: 26392221 Free PMC article.
The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain.
Jiang Y, Loh YE, Rajarajan P, Hirayama T, Liao W, Kassim BS, Javidfar B, Hartley BJ, Kleofas L, Park RB, Labonte B, Ho SM, Chandrasekaran S, Do C, Ramirez BR, Peter CJ, C W JT, Safaie BM, Morishita H, Roussos P, Nestler EJ, Schaefer A, Tycko B, Brennand KJ, Yagi T, Shen L, Akbarian S. Jiang Y, et al. Among authors: schaefer a. Nat Genet. 2017 Aug;49(8):1239-1250. doi: 10.1038/ng.3906. Epub 2017 Jul 3. Nat Genet. 2017. PMID: 28671686 Free PMC article.
1,249 results