Hill AP - Search Results

1

T-wave morphology can distinguish healthy controls from LQTS patients.

Immanuel SA, Sadrieh A, Baumert M, Couderc JP, Zareba W, Hill AP, Vandenberg JI. Immanuel SA, et al. Among authors: hill ap. Physiol Meas. 2016 Sep;37(9):1456-73. doi: 10.1088/0967-3334/37/9/1456. Epub 2016 Aug 11. Physiol Meas. 2016. PMID: 27510854

2

Effect of S5P alpha-helix charge mutants on inactivation of hERG K+ channels.

Clarke CE, Hill AP, Zhao J, Kondo M, Subbiah RN, Campbell TJ, Vandenberg JI. Clarke CE, et al. Among authors: hill ap. J Physiol. 2006 Jun 1;573(Pt 2):291-304. doi: 10.1113/jphysiol.2006.108332. Epub 2006 Mar 23. J Physiol. 2006. PMID: 16556651 Free PMC article.

3

Mechanism of block of the hERG K+ channel by the scorpion toxin CnErg1.

Hill AP, Sunde M, Campbell TJ, Vandenberg JI. Hill AP, et al. Biophys J. 2007 Jun 1;92(11):3915-29. doi: 10.1529/biophysj.106.101956. Epub 2007 Mar 16. Biophys J. 2007. PMID: 17369411 Free PMC article.

4

The S631A mutation causes a mechanistic switch in the block of hERG channels by CnErg1.

Hill AP, Campbell TJ, Bansal PS, Kuchel PW, Vandenberg JI. Hill AP, et al. Biophys J. 2007 Sep 15;93(6):L32-4. doi: 10.1529/biophysj.107.114561. Epub 2007 Jul 13. Biophys J. 2007. PMID: 17631536 Free PMC article.

5

Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.

Perrin MJ, Subbiah RN, Vandenberg JI, Hill AP. Perrin MJ, et al. Among authors: hill ap. Prog Biophys Mol Biol. 2008 Oct-Nov;98(2-3):137-48. doi: 10.1016/j.pbiomolbio.2008.10.006. Epub 2008 Nov 5. Prog Biophys Mol Biol. 2008. PMID: 19027781 Free article. Review.

6

Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype.

Zhao JT, Hill AP, Varghese A, Cooper AA, Swan H, Laitinen-Forsblom PJ, Rees MI, Skinner JR, Campbell TJ, Vandenberg JI. Zhao JT, et al. Among authors: hill ap. J Cardiovasc Electrophysiol. 2009 Aug;20(8):923-30. doi: 10.1111/j.1540-8167.2009.01468.x. Epub 2009 Apr 10. J Cardiovasc Electrophysiol. 2009. PMID: 19490267

7

Domain reorientation and rotation of an intracellular assembly regulate conduction in Kir potassium channels.

Clarke OB, Caputo AT, Hill AP, Vandenberg JI, Smith BJ, Gulbis JM. Clarke OB, et al. Among authors: hill ap. Cell. 2010 Jun 11;141(6):1018-29. doi: 10.1016/j.cell.2010.05.003. Cell. 2010. PMID: 20564790 Free article.

8

An improved curvilinear gradient method for parameter optimization in complex biological models.

Szekely D, Vandenberg JI, Dokos S, Hill AP. Szekely D, et al. Among authors: hill ap. Med Biol Eng Comput. 2011 Mar;49(3):289-96. doi: 10.1007/s11517-010-0667-1. Epub 2010 Jul 30. Med Biol Eng Comput. 2011. PMID: 20676939

9

Mapping the sequence of conformational changes underlying selectivity filter gating in the K(v)11.1 potassium channel.

Wang DT, Hill AP, Mann SA, Tan PS, Vandenberg JI. Wang DT, et al. Among authors: hill ap. Nat Struct Mol Biol. 2011 Jan;18(1):35-41. doi: 10.1038/nsmb.1966. Epub 2010 Dec 19. Nat Struct Mol Biol. 2011. PMID: 21170050

10

The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating.

Ng CA, Perry MD, Tan PS, Hill AP, Kuchel PW, Vandenberg JI. Ng CA, et al. Among authors: hill ap. PLoS One. 2012;7(2):e31640. doi: 10.1371/journal.pone.0031640. Epub 2012 Feb 16. PLoS One. 2012. PMID: 22359612 Free PMC article.

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