Kashuba AD - Search Results

1

Randomized Pharmacokinetic Crossover Study Comparing 2 Curcumin Preparations in Plasma and Rectal Tissue of Healthy Human Volunteers.

Asher GN, Xie Y, Moaddel R, Sanghvi M, Dossou KS, Kashuba AD, Sandler RS, Hawke RL. Asher GN, et al. Among authors: kashuba ad. J Clin Pharmacol. 2017 Feb;57(2):185-193. doi: 10.1002/jcph.806. Epub 2016 Sep 6. J Clin Pharmacol. 2017. PMID: 27503249 Free PMC article. Clinical Trial.

2

Kupffer cell-mediated IL-2 suppression of CYP3A activity in human hepatocytes.

Sunman JA, Hawke RL, LeCluyse EL, Kashuba AD. Sunman JA, et al. Among authors: kashuba ad. Drug Metab Dispos. 2004 Mar;32(3):359-63. doi: 10.1124/dmd.32.3.359. Drug Metab Dispos. 2004. PMID: 14977871

3

Poor correlation between 6beta-hydroxycortisol:cortisol molar ratios and midazolam clearance as measure of hepatic CYP3A activity.

Chen YC, Gotzkowsky SK, Nafziger AN, Kulawy RW, Rocci ML Jr, Bertino JS Jr, Kashuba AD. Chen YC, et al. Among authors: kashuba ad. Br J Clin Pharmacol. 2006 Aug;62(2):187-95. doi: 10.1111/j.1365-2125.2006.02628.x. Br J Clin Pharmacol. 2006. PMID: 16842393 Free PMC article.

4

Lopinavir/ritonavir reduces bupropion plasma concentrations in healthy subjects.

Hogeland GW, Swindells S, McNabb JC, Kashuba AD, Yee GC, Lindley CM. Hogeland GW, et al. Among authors: kashuba ad. Clin Pharmacol Ther. 2007 Jan;81(1):69-75. doi: 10.1038/sj.clpt.6100027. Clin Pharmacol Ther. 2007. PMID: 17186001 Clinical Trial.

5

The influence of CYP3A5 genotype on dexamethasone induction of CYP3A activity in African Americans.

Roberts PJ, Rollins KD, Kashuba AD, Paine MF, Nelsen AC, Williams EE, Moran C, Lamba JK, Schuetz EG, Hawke RL. Roberts PJ, et al. Among authors: kashuba ad. Drug Metab Dispos. 2008 Aug;36(8):1465-9. doi: 10.1124/dmd.107.020065. Epub 2008 May 19. Drug Metab Dispos. 2008. PMID: 18490434 Free PMC article.

6

The pharmacokinetics of silymarin is altered in patients with hepatitis C virus and nonalcoholic Fatty liver disease and correlates with plasma caspase-3/7 activity.

Schrieber SJ, Wen Z, Vourvahis M, Smith PC, Fried MW, Kashuba AD, Hawke RL. Schrieber SJ, et al. Among authors: kashuba ad. Drug Metab Dispos. 2008 Sep;36(9):1909-16. doi: 10.1124/dmd.107.019604. Epub 2008 Jun 19. Drug Metab Dispos. 2008. PMID: 18566043 Clinical Trial.

7

A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.

Dumond JB, Vourvahis M, Rezk NL, Patterson KB, Tien HC, White N, Jennings SH, Choi SO, Li J, Wagner MJ, La-Beck NM, Drulak M, Sabo JP, Castles MA, Macgregor TR, Kashuba AD. Dumond JB, et al. Among authors: kashuba ad. Clin Pharmacol Ther. 2010 Jun;87(6):735-42. doi: 10.1038/clpt.2009.253. Epub 2010 Feb 10. Clin Pharmacol Ther. 2010. PMID: 20147896 Free PMC article. Clinical Trial.

8

Pharmacologic opportunities for HIV prevention.

Nicol MR, Kashuba AD. Nicol MR, et al. Among authors: kashuba ad. Clin Pharmacol Ther. 2010 Nov;88(5):598-609. doi: 10.1038/clpt.2010.189. Epub 2010 Sep 29. Clin Pharmacol Ther. 2010. PMID: 20881955 Free PMC article. Review.

9

Single and multiple dose pharmacokinetics of maraviroc in saliva, semen, and rectal tissue of healthy HIV-negative men.

Brown KC, Patterson KB, Malone SA, Shaheen NJ, Prince HM, Dumond JB, Spacek MB, Heidt PE, Cohen MS, Kashuba AD. Brown KC, et al. Among authors: kashuba ad. J Infect Dis. 2011 May 15;203(10):1484-90. doi: 10.1093/infdis/jir059. J Infect Dis. 2011. PMID: 21502084 Free PMC article.

10

The influence of sex, ethnicity, and CYP2B6 genotype on bupropion metabolism as an index of hepatic CYP2B6 activity in humans.

Ilic K, Hawke RL, Thirumaran RK, Schuetz EG, Hull JH, Kashuba AD, Stewart PW, Lindley CM, Chen ML. Ilic K, et al. Among authors: kashuba ad. Drug Metab Dispos. 2013 Mar;41(3):575-81. doi: 10.1124/dmd.112.048108. Epub 2012 Dec 13. Drug Metab Dispos. 2013. PMID: 23238783 Free PMC article.

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