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Pioglitazone's beneficial effects on erectile function preservation after cavernosal nerve injury in the rat are negated by inhibition of the insulin-like growth factor-1 receptor: a preclinical study.
Heidenberg DJ, Haney NM, Rezk BM, Talwar S, Okpechi SC, Srivastav SK, Honda M, Song B, Swan K, Awadallah S, Anaissie J, Peak T, DeLay KJ, Kadowitz PJ, Sikka SC, Abdel Mageed AB, Hellstrom WJG. Heidenberg DJ, et al. Among authors: talwar s. Int J Impot Res. 2019 Jan;31(1):1-8. doi: 10.1038/s41443-018-0054-2. Epub 2018 Aug 2. Int J Impot Res. 2019. PMID: 30072768
Insulin-Like Growth Factor-1-Loaded Polymeric Poly(Lactic-Co-Glycolic) Acid Microspheres Improved Erectile Function in a Rat Model of Bilateral Cavernous Nerve Injury.
Haney NM, Talwar S, Akula PK, Reddy AG, Pema GS, Ninh TV, Rezk BM, Heidari Z, Bouljihad MT, Sikka SC, John V, Abdel-Mageed AB, Hellstrom WJG. Haney NM, et al. Among authors: talwar s. J Sex Med. 2019 Mar;16(3):383-393. doi: 10.1016/j.jsxm.2018.12.018. J Sex Med. 2019. PMID: 30846112
CONCLUSION: Stimulating the IGF-1R at the level of the CN has the potential to mitigate erectile dysfunction in men after radical prostatectomy, but further research is needed to evaluate the safety of this growth factor in the setting of prostate cancer. Haney NM, Talwar …
CONCLUSION: Stimulating the IGF-1R at the level of the CN has the potential to mitigate erectile dysfunction in men after radical prostatect …
591 results