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267 results

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Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells.
Kebriaei P, Singh H, Huls MH, Figliola MJ, Bassett R, Olivares S, Jena B, Dawson MJ, Kumaresan PR, Su S, Maiti S, Dai J, Moriarity B, Forget MA, Senyukov V, Orozco A, Liu T, McCarty J, Jackson RN, Moyes JS, Rondon G, Qazilbash M, Ciurea S, Alousi A, Nieto Y, Rezvani K, Marin D, Popat U, Hosing C, Shpall EJ, Kantarjian H, Keating M, Wierda W, Do KA, Largaespada DA, Lee DA, Hackett PB, Champlin RE, Cooper LJ. Kebriaei P, et al. Among authors: jena b. J Clin Invest. 2016 Sep 1;126(9):3363-76. doi: 10.1172/JCI86721. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482888 Free PMC article. Clinical Trial.
Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies.
Kebriaei P, Huls H, Jena B, Munsell M, Jackson R, Lee DA, Hackett PB, Rondon G, Shpall E, Champlin RE, Cooper LJ. Kebriaei P, et al. Among authors: jena b. Hum Gene Ther. 2012 May;23(5):444-50. doi: 10.1089/hum.2011.167. Epub 2012 Jan 17. Hum Gene Ther. 2012. PMID: 22107246 Free PMC article. Clinical Trial.
Manufacture of clinical-grade CD19-specific T cells stably expressing chimeric antigen receptor using Sleeping Beauty system and artificial antigen presenting cells.
Singh H, Figliola MJ, Dawson MJ, Olivares S, Zhang L, Yang G, Maiti S, Manuri P, Senyukov V, Jena B, Kebriaei P, Champlin RE, Huls H, Cooper LJ. Singh H, et al. Among authors: jena b. PLoS One. 2013 May 31;8(5):e64138. doi: 10.1371/journal.pone.0064138. Print 2013. PLoS One. 2013. PMID: 23741305 Free PMC article.
Driving CAR-based T-cell therapy to success.
Jena B, Moyes JS, Huls H, Cooper LJ. Jena B, et al. Curr Hematol Malig Rep. 2014 Mar;9(1):50-6. doi: 10.1007/s11899-013-0197-7. Curr Hematol Malig Rep. 2014. PMID: 24488441 Free PMC article. Review.
CARs in chronic lymphocytic leukemia -- ready to drive.
Hosing C, Kebriaei P, Wierda W, Jena B, Cooper LJN, Shpall E. Hosing C, et al. Among authors: jena b. Curr Hematol Malig Rep. 2013 Mar;8(1):60-70. doi: 10.1007/s11899-012-0145-y. Curr Hematol Malig Rep. 2013. PMID: 23225251 Free PMC article. Review.
CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo.
Tian G, Courtney AN, Jena B, Heczey A, Liu D, Marinova E, Guo L, Xu X, Torikai H, Mo Q, Dotti G, Cooper LJ, Metelitsa LS. Tian G, et al. Among authors: jena b. J Clin Invest. 2016 Jun 1;126(6):2341-55. doi: 10.1172/JCI83476. Epub 2016 May 16. J Clin Invest. 2016. PMID: 27183388 Free PMC article.
267 results