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Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells.
Kebriaei P, Singh H, Huls MH, Figliola MJ, Bassett R, Olivares S, Jena B, Dawson MJ, Kumaresan PR, Su S, Maiti S, Dai J, Moriarity B, Forget MA, Senyukov V, Orozco A, Liu T, McCarty J, Jackson RN, Moyes JS, Rondon G, Qazilbash M, Ciurea S, Alousi A, Nieto Y, Rezvani K, Marin D, Popat U, Hosing C, Shpall EJ, Kantarjian H, Keating M, Wierda W, Do KA, Largaespada DA, Lee DA, Hackett PB, Champlin RE, Cooper LJ. Kebriaei P, et al. Among authors: huls mh. J Clin Invest. 2016 Sep 1;126(9):3363-76. doi: 10.1172/JCI86721. Epub 2016 Aug 2. J Clin Invest. 2016. PMID: 27482888 Free PMC article. Clinical Trial.
Sleeping Beauty Transposition of Chimeric Antigen Receptors Targeting Receptor Tyrosine Kinase-Like Orphan Receptor-1 (ROR1) into Diverse Memory T-Cell Populations.
Deniger DC, Yu J, Huls MH, Figliola MJ, Mi T, Maiti SN, Widhopf GF 2nd, Hurton LV, Thokala R, Singh H, Olivares S, Champlin RE, Wierda WG, Kipps TJ, Cooper LJ. Deniger DC, et al. Among authors: huls mh. PLoS One. 2015 Jun 1;10(6):e0128151. doi: 10.1371/journal.pone.0128151. eCollection 2015. PLoS One. 2015. PMID: 26030772 Free PMC article.
Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection.
Kumaresan PR, Manuri PR, Albert ND, Maiti S, Singh H, Mi T, Roszik J, Rabinovich B, Olivares S, Krishnamurthy J, Zhang L, Najjar AM, Huls MH, Lee DA, Champlin RE, Kontoyiannis DP, Cooper LJ. Kumaresan PR, et al. Among authors: huls mh. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):10660-5. doi: 10.1073/pnas.1312789111. Epub 2014 Jul 7. Proc Natl Acad Sci U S A. 2014. PMID: 25002471 Free PMC article.
Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes.
Straathof KC, Bollard CM, Popat U, Huls MH, Lopez T, Morriss MC, Gresik MV, Gee AP, Russell HV, Brenner MK, Rooney CM, Heslop HE. Straathof KC, et al. Among authors: huls mh. Blood. 2005 Mar 1;105(5):1898-904. doi: 10.1182/blood-2004-07-2975. Epub 2004 Nov 12. Blood. 2005. PMID: 15542583 Free article. Clinical Trial.
40 results