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Comparison of targeted next-generation sequencing (NGS) and real-time PCR in the detection of EGFR, KRAS, and BRAF mutations on formalin-fixed, paraffin-embedded tumor material of non-small cell lung carcinoma-superiority of NGS.
Tuononen K, Mäki-Nevala S, Sarhadi VK, Wirtanen A, Rönty M, Salmenkivi K, Andrews JM, Telaranta-Keerie AI, Hannula S, Lagström S, Ellonen P, Knuuttila A, Knuutila S. Tuononen K, et al. Among authors: knuutila s. Genes Chromosomes Cancer. 2013 May;52(5):503-11. doi: 10.1002/gcc.22047. Epub 2013 Jan 30. Genes Chromosomes Cancer. 2013. PMID: 23362162
MicroRNA profiling differentiates colorectal cancer according to KRAS status.
Mosakhani N, Sarhadi VK, Borze I, Karjalainen-Lindsberg ML, Sundström J, Ristamäki R, Osterlund P, Knuutila S. Mosakhani N, et al. Among authors: knuutila s. Genes Chromosomes Cancer. 2012 Jan;51(1):1-9. doi: 10.1002/gcc.20925. Epub 2011 Sep 15. Genes Chromosomes Cancer. 2012. PMID: 21922590
The hypermethylation of the O6-methylguanine-DNA methyltransferase gene promoter in gliomas--correlation with array comparative genome hybridization results and IDH1 mutation.
Tuononen K, Tynninen O, Sarhadi VK, Tyybäkinoja A, Lindlöf M, Antikainen M, Näpänkangas J, Hirvonen A, Mäenpää H, Paetau A, Knuutila S. Tuononen K, et al. Among authors: knuutila s. Genes Chromosomes Cancer. 2012 Jan;51(1):20-9. doi: 10.1002/gcc.20927. Epub 2011 Sep 15. Genes Chromosomes Cancer. 2012. PMID: 21922591
Mutated ephrin receptor genes in non-small cell lung carcinoma and their occurrence with driver mutations-targeted resequencing study on formalin-fixed, paraffin-embedded tumor material of 81 patients.
Mäki-Nevala S, Kaur Sarhadi V, Tuononen K, Lagström S, Ellonen P, Rönty M, Wirtanen A, Knuuttila A, Knuutila S. Mäki-Nevala S, et al. Among authors: knuutila s. Genes Chromosomes Cancer. 2013 Dec;52(12):1141-9. doi: 10.1002/gcc.22109. Epub 2013 Oct 7. Genes Chromosomes Cancer. 2013. PMID: 24123310
536 results