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Leptin-replacement therapy for lipodystrophy.
Oral EA, Simha V, Ruiz E, Andewelt A, Premkumar A, Snell P, Wagner AJ, DePaoli AM, Reitman ML, Taylor SI, Gorden P, Garg A. Oral EA, et al. Among authors: reitman ml. N Engl J Med. 2002 Feb 21;346(8):570-8. doi: 10.1056/NEJMoa012437. N Engl J Med. 2002. PMID: 11856796 Free article. Clinical Trial.
Biphasic effect of melanocortin agonists on metabolic rate and body temperature.
Lute B, Jou W, Lateef DM, Goldgof M, Xiao C, Piñol RA, Kravitz AV, Miller NR, Huang YG, Girardet C, Butler AA, Gavrilova O, Reitman ML. Lute B, et al. Among authors: reitman ml. Cell Metab. 2014 Aug 5;20(2):333-45. doi: 10.1016/j.cmet.2014.05.021. Epub 2014 Jun 26. Cell Metab. 2014. PMID: 24981835 Free PMC article.
RM-493, a melanocortin-4 receptor (MC4R) agonist, increases resting energy expenditure in obese individuals.
Chen KY, Muniyappa R, Abel BS, Mullins KP, Staker P, Brychta RJ, Zhao X, Ring M, Psota TL, Cone RD, Panaro BL, Gottesdiener KM, Van der Ploeg LH, Reitman ML, Skarulis MC. Chen KY, et al. Among authors: reitman ml. J Clin Endocrinol Metab. 2015 Apr;100(4):1639-45. doi: 10.1210/jc.2014-4024. Epub 2015 Feb 12. J Clin Endocrinol Metab. 2015. PMID: 25675384 Free PMC article. Clinical Trial.
FGF21 mimetic shows therapeutic promise.
Reitman ML. Reitman ML. Cell Metab. 2013 Sep 3;18(3):307-9. doi: 10.1016/j.cmet.2013.08.014. Cell Metab. 2013. PMID: 24011067 Free PMC article.
172 results