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Rev-Erbs repress macrophage gene expression by inhibiting enhancer-directed transcription.
Lam MT, Cho H, Lesch HP, Gosselin D, Heinz S, Tanaka-Oishi Y, Benner C, Kaikkonen MU, Kim AS, Kosaka M, Lee CY, Watt A, Grossman TR, Rosenfeld MG, Evans RM, Glass CK. Lam MT, et al. Among authors: lesch hp. Nature. 2013 Jun 27;498(7455):511-5. doi: 10.1038/nature12209. Epub 2013 Jun 2. Nature. 2013. PMID: 23728303 Free PMC article.
Avidin-biotin technology in targeted therapy.
Lesch HP, Kaikkonen MU, Pikkarainen JT, Ylä-Herttuala S. Lesch HP, et al. Expert Opin Drug Deliv. 2010 May;7(5):551-64. doi: 10.1517/17425241003677749. Expert Opin Drug Deliv. 2010. PMID: 20233034 Review.
Differential Promoter Methylation of Macrophage Genes Is Associated With Impaired Vascular Growth in Ischemic Muscles of Hyperlipidemic and Type 2 Diabetic Mice: Genome-Wide Promoter Methylation Study.
Babu M, Durga Devi T, Mäkinen P, Kaikkonen M, Lesch HP, Junttila S, Laiho A, Ghimire B, Gyenesei A, Ylä-Herttuala S. Babu M, et al. Among authors: lesch hp. Circ Res. 2015 Jul 17;117(3):289-99. doi: 10.1161/CIRCRESAHA.115.306424. Epub 2015 Jun 17. Circ Res. 2015. PMID: 26085133
Biodistribution and antitumor effect of Cetuximab-targeted lentivirus.
Huhtala T, Kaikkonen MU, Lesch HP, Viitala S, Ylä-Herttuala S, Närvänen A. Huhtala T, et al. Among authors: lesch hp. Nucl Med Biol. 2014 Jan;41(1):77-83. doi: 10.1016/j.nucmedbio.2013.10.005. Epub 2013 Oct 18. Nucl Med Biol. 2014. PMID: 24267054
Oxidative stress-regulated lentiviral TK/GCV gene therapy for lung cancer treatment.
Leinonen HM, Ruotsalainen AK, Määttä AM, Laitinen HM, Kuosmanen SM, Kansanen E, Pikkarainen JT, Lappalainen JP, Samaranayake H, Lesch HP, Kaikkonen MU, Ylä-Herttuala S, Levonen AL. Leinonen HM, et al. Among authors: lesch hp. Cancer Res. 2012 Dec 1;72(23):6227-35. doi: 10.1158/0008-5472.CAN-12-1166. Epub 2012 Oct 4. Cancer Res. 2012. PMID: 23041549
Targeted delivery via avidin fusion protein: intracellular fate of biotinylated doxorubicin derivative and cellular uptake kinetics and biodistribution of biotinylated liposomes.
Soininen SK, Lehtolainen-Dalkilic P, Karppinen T, Puustinen T, Dragneva G, Kaikkonen MU, Jauhiainen M, Allart B, Selwood DL, Wirth T, Lesch HP, Määttä AM, Mönkkönen J, Ylä-Herttuala S, Ruponen M. Soininen SK, et al. Among authors: lesch hp. Eur J Pharm Sci. 2012 Dec 18;47(5):848-56. doi: 10.1016/j.ejps.2012.09.001. Epub 2012 Sep 14. Eur J Pharm Sci. 2012. PMID: 22985874
33 results