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In situ prolyl oligopeptidase activity assay in neural cell cultures.
Klimaviciusa L, Jain RK, Jaako K, Van Elzen R, Gerard M, van Der Veken P, Lambeir AM, Zharkovsky A. Klimaviciusa L, et al. Among authors: van der veken p, van elzen r. J Neurosci Methods. 2012 Feb 15;204(1):104-110. doi: 10.1016/j.jneumeth.2011.11.011. Epub 2011 Nov 11. J Neurosci Methods. 2012. PMID: 22101193
A prolyl oligopeptidase inhibitor, KYP-2047, reduces α-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease.
Myöhänen TT, Hannula MJ, Van Elzen R, Gerard M, Van Der Veken P, García-Horsman JA, Baekelandt V, Männistö PT, Lambeir AM. Myöhänen TT, et al. Among authors: van der veken p, van elzen r. Br J Pharmacol. 2012 Jun;166(3):1097-113. doi: 10.1111/j.1476-5381.2012.01846.x. Br J Pharmacol. 2012. PMID: 22233220 Free PMC article.
P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy.
Van der Veken P, Fülöp V, Rea D, Gerard M, Van Elzen R, Joossens J, Cheng JD, Baekelandt V, De Meester I, Lambeir AM, Augustyns K. Van der Veken P, et al. Among authors: van elzen r. J Med Chem. 2012 Nov 26;55(22):9856-67. doi: 10.1021/jm301060g. Epub 2012 Nov 13. J Med Chem. 2012. PMID: 23121075
Dysregulation of the renin-angiotensin system during lung ischemia-reperfusion injury.
Kehoe K, Gielis JF, Vliegen G, Van Elzen R, Verkerk R, Driessens E, Domen A, Lambeir AM, Maes L, Cos P, De Meester I, Van Schil PE. Kehoe K, et al. Among authors: van schil pe, van elzen r. Exp Lung Res. 2016 Aug;42(6):277-85. doi: 10.1080/01902148.2016.1207725. Epub 2016 Jul 20. Exp Lung Res. 2016. PMID: 27437782
20 results