Zeckner DJ - Search Results

1

Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth.

Smith MC, Mader MM, Cook JA, Iversen P, Ajamie R, Perkins E, Bloem L, Yip YY, Barda DA, Waid PP, Zeckner DJ, Young DA, Sanchez-Felix M, Donoho GP, Wacheck V. Smith MC, et al. Among authors: zeckner dj. Mol Cancer Ther. 2016 Oct;15(10):2344-2356. doi: 10.1158/1535-7163.MCT-15-0996. Epub 2016 Jul 20. Mol Cancer Ther. 2016. PMID: 27439478

2

A novel CDK9 inhibitor shows potent antitumor efficacy in preclinical hematologic tumor models.

Yin T, Lallena MJ, Kreklau EL, Fales KR, Carballares S, Torrres R, Wishart GN, Ajamie RT, Cronier DM, Iversen PW, Meier TI, Foreman RT, Zeckner D, Sissons SE, Halstead BW, Lin AB, Donoho GP, Qian Y, Li S, Wu S, Aggarwal A, Ye XS, Starling JJ, Gaynor RB, de Dios A, Du J. Yin T, et al. Mol Cancer Ther. 2014 Jun;13(6):1442-56. doi: 10.1158/1535-7163.MCT-13-0849. Epub 2014 Mar 31. Mol Cancer Ther. 2014. PMID: 24688048

3

A transforming mutation in the pleckstrin homology domain of AKT1 in cancer.

Carpten JD, Faber AL, Horn C, Donoho GP, Briggs SL, Robbins CM, Hostetter G, Boguslawski S, Moses TY, Savage S, Uhlik M, Lin A, Du J, Qian YW, Zeckner DJ, Tucker-Kellogg G, Touchman J, Patel K, Mousses S, Bittner M, Schevitz R, Lai MH, Blanchard KL, Thomas JE. Carpten JD, et al. Among authors: zeckner dj. Nature. 2007 Jul 26;448(7152):439-44. doi: 10.1038/nature05933. Epub 2007 Jul 4. Nature. 2007. PMID: 17611497

4

Synthesis and evaluation of oxodioxolenylmethyl carbamate prodrugs of pseudomycins.

Sun X, Rodriguez M, Zeckner D, Sachs B, Current W, Boyer R, Paschal J, McMillian C, Chen SH. Sun X, et al. J Med Chem. 2001 Aug 2;44(16):2671-4. doi: 10.1021/jm000425w. J Med Chem. 2001. PMID: 11472220

5

N-acyloxymethyl carbamate linked prodrugs of pseudomycins are novel antifungal agents.

Sun X, Zeckner DJ, Current WL, Boyer R, McMillian C, Yumibe N, Chen SH. Sun X, et al. Among authors: zeckner dj. Bioorg Med Chem Lett. 2001 Jul 23;11(14):1875-9. doi: 10.1016/s0960-894x(01)00333-x. Bioorg Med Chem Lett. 2001. PMID: 11459651

6

Syntheses and antifungal activity of pseudomycin side-chain analogues. Part 1.

Jamison J, Levy S, Sun X, Zeckner D, Current W, Zweifel M, Rodriguez M, Turner W, Chen SH. Jamison J, et al. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2101-5. doi: 10.1016/s0960-894x(00)00423-6. Bioorg Med Chem Lett. 2000. PMID: 10999480

7

Syntheses and biological evaluation of novel pseudomycin side-chain analogues. Part 2.

Chen SH, Sun X, Boyer R, Paschal J, Zeckner D, Current W, Zweifel M, Rodriguez M. Chen SH, et al. Bioorg Med Chem Lett. 2000 Sep 18;10(18):2107-10. doi: 10.1016/s0960-894x(00)00424-8. Bioorg Med Chem Lett. 2000. PMID: 10999481

8

Synthesis and evaluation of novel pseudomycin side-chain analogues. Part 3.

Sun X, Zhang YZ, Zeckner D, Current W, Chen SH. Sun X, et al. Bioorg Med Chem Lett. 2001 Dec 3;11(23):3055-9. doi: 10.1016/s0960-894x(01)00627-8. Bioorg Med Chem Lett. 2001. PMID: 11714609

9

8-Amido-Bearing pseudomycin B (PSB) analogue: novel antifungal agents.

Zhang YZ, Sun X, Zeckner DJ, Sachs RK, Current WL, Chen SH. Zhang YZ, et al. Among authors: zeckner dj. Bioorg Med Chem Lett. 2001 Jan 22;11(2):123-6. doi: 10.1016/s0960-894x(00)00606-5. Bioorg Med Chem Lett. 2001. PMID: 11206441

10

Syntheses and antifungal activities of novel 3-amido bearing pseudomycin analogues.

Zhang YZ, Sun X, Zeckner DJ, Sachs RK, Current WL, Gidda J, Rodriguez M, Chen SH. Zhang YZ, et al. Among authors: zeckner dj. Bioorg Med Chem Lett. 2001 Apr 9;11(7):903-7. doi: 10.1016/s0960-894x(01)00101-9. Bioorg Med Chem Lett. 2001. PMID: 11294388

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