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Characterization of LY3023414, a Novel PI3K/mTOR Dual Inhibitor Eliciting Transient Target Modulation to Impede Tumor Growth.
Smith MC, Mader MM, Cook JA, Iversen P, Ajamie R, Perkins E, Bloem L, Yip YY, Barda DA, Waid PP, Zeckner DJ, Young DA, Sanchez-Felix M, Donoho GP, Wacheck V. Smith MC, et al. Among authors: young da. Mol Cancer Ther. 2016 Oct;15(10):2344-2356. doi: 10.1158/1535-7163.MCT-15-0996. Epub 2016 Jul 20. Mol Cancer Ther. 2016. PMID: 27439478
Pharmacological inhibition of nicotinamide phosphoribosyltransferase (NAMPT), an enzyme essential for NAD+ biosynthesis, in human cancer cells: metabolic basis and potential clinical implications.
Tan B, Young DA, Lu ZH, Wang T, Meier TI, Shepard RL, Roth K, Zhai Y, Huss K, Kuo MS, Gillig J, Parthasarathy S, Burkholder TP, Smith MC, Geeganage S, Zhao G. Tan B, et al. Among authors: young da. J Biol Chem. 2013 Feb 1;288(5):3500-11. doi: 10.1074/jbc.M112.394510. Epub 2012 Dec 13. J Biol Chem. 2013. PMID: 23239881 Free PMC article.
Epigenetic mechanisms of osteoarthritis risk in human skeletal development.
McDonnell E, Orr SE, Barter MJ, Rux D, Brumwell A, Wrobel N, Murphy L, Overmann LM, Sorial AK, Young DA, Soul J, Rice SJ. McDonnell E, et al. Among authors: young da. medRxiv [Preprint]. 2024 May 6:2024.05.05.24306832. doi: 10.1101/2024.05.05.24306832. medRxiv. 2024. PMID: 38766055 Free PMC article. Preprint.
An ancient river landscape preserved beneath the East Antarctic Ice Sheet.
Jamieson SSR, Ross N, Paxman GJG, Clubb FJ, Young DA, Yan S, Greenbaum J, Blankenship DD, Siegert MJ. Jamieson SSR, et al. Among authors: young da. Nat Commun. 2023 Oct 24;14(1):6507. doi: 10.1038/s41467-023-42152-2. Nat Commun. 2023. PMID: 37875503 Free PMC article.
Birmingham Hip Resurfacing at 20 years.
Dhawan R, Young DA, Van Eemeren A, Shimmin A. Dhawan R, et al. Among authors: young da. Bone Joint J. 2023 Sep 1;105-B(9):946-952. doi: 10.1302/0301-620X.105B9.BJJ-2022-0713.R2. Bone Joint J. 2023. PMID: 37652450
517 results