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Pharmacological evaluation of pioglitazone and candesartan cilexetil in a novel mouse model of non-alcoholic steatohepatitis, modified choline-deficient, amino acid-defined diet fed low-density lipoprotein receptor knockout mice.
Tsuchiya S, Amano Y, Isono O, Imai M, Shimizu F, Asada M, Imai S, Harada A, Yasuhara Y, Tozawa R, Nagabukuro H. Tsuchiya S, et al. Among authors: harada a. Hepatol Res. 2017 May;47(6):584-592. doi: 10.1111/hepr.12773. Epub 2016 Aug 17. Hepatol Res. 2017. PMID: 27421062
TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats.
Tsujihata Y, Ito R, Suzuki M, Harada A, Negoro N, Yasuma T, Momose Y, Takeuchi K. Tsujihata Y, et al. Among authors: harada a. J Pharmacol Exp Ther. 2011 Oct;339(1):228-37. doi: 10.1124/jpet.111.183772. Epub 2011 Jul 13. J Pharmacol Exp Ther. 2011. PMID: 21752941
Discovery of TAK-875: A Potent, Selective, and Orally Bioavailable GPR40 Agonist.
Negoro N, Sasaki S, Mikami S, Ito M, Suzuki M, Tsujihata Y, Ito R, Harada A, Takeuchi K, Suzuki N, Miyazaki J, Santou T, Odani T, Kanzaki N, Funami M, Tanaka T, Kogame A, Matsunaga S, Yasuma T, Momose Y. Negoro N, et al. Among authors: harada a. ACS Med Chem Lett. 2010 Jun 18;1(6):290-4. doi: 10.1021/ml1000855. eCollection 2010 Sep 9. ACS Med Chem Lett. 2010. PMID: 24900210 Free PMC article.
Dynamic movement of the Golgi unit and its glycosylation enzyme zones.
Harada A, Kunii M, Kurokawa K, Sumi T, Kanda S, Zhang Y, Nadanaka S, Hirosawa KM, Tokunaga K, Tojima T, Taniguchi M, Moriwaki K, Yoshimura SI, Yamamoto-Hino M, Goto S, Katagiri T, Kume S, Hayashi-Nishino M, Nakano M, Miyoshi E, Suzuki KGN, Kitagawa H, Nakano A. Harada A, et al. Nat Commun. 2024 May 27;15(1):4514. doi: 10.1038/s41467-024-48901-1. Nat Commun. 2024. PMID: 38802491 Free PMC article.
Skeletal Myoblast Cells Enhance the Function of Transplanted Islets in Diabetic Mice.
Kado T, Tomimaru Y, Kobayashi S, Harada A, Sasaki K, Iwagami Y, Yamada D, Noda T, Takahashi H, Kita S, Shimomura I, Miyagawa S, Doki Y, Eguchi H. Kado T, et al. Among authors: harada a. J Diabetes Res. 2024 May 17;2024:5574968. doi: 10.1155/2024/5574968. eCollection 2024. J Diabetes Res. 2024. PMID: 38800586 Free PMC article.
Precise immunofluorescence canceling for highly multiplexed imaging to capture specific cell states.
Tomimatsu K, Fujii T, Bise R, Hosoda K, Taniguchi Y, Ochiai H, Ohishi H, Ando K, Minami R, Tanaka K, Tachibana T, Mori S, Harada A, Maehara K, Nagasaki M, Uchida S, Kimura H, Narita M, Ohkawa Y. Tomimatsu K, et al. Among authors: harada a. Nat Commun. 2024 May 8;15(1):3657. doi: 10.1038/s41467-024-47989-9. Nat Commun. 2024. PMID: 38719795 Free PMC article.
1,403 results