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Morphological and molecular features of astroblastoma, including BRAFV600E mutations, suggest an ontological relationship to other cortical-based gliomas of children and young adults.
Lehman NL, Hattab EM, Mobley BC, Usubalieva A, Schniederjan MJ, McLendon RE, Paulus W, Rushing EJ, Georgescu MM, Couce M, Dulai MS, Cohen ML, Pierson CR, Raisanen JM, Martin SE, Lehman TD, Lipp ES, Bonnin JM, Al-Abbadi MA, Kenworthy K, Zhao K, Mohamed N, Zhang G, Zhao W. Lehman NL, et al. Among authors: lehman td. Neuro Oncol. 2017 Jan;19(1):31-42. doi: 10.1093/neuonc/now118. Epub 2016 Jul 14. Neuro Oncol. 2017. PMID: 27416954 Free PMC article.
Gliosarcoma with melanocytic differentiation.
Dulai MS, Moes GS, Briley AL, Galperin IB, Smyth L, Cherry AM, Lehman NL. Dulai MS, et al. Among authors: lehman nl. Acta Neuropathol. 2008 Mar;115(3):357-61. doi: 10.1007/s00401-007-0232-7. Epub 2007 Jul 20. Acta Neuropathol. 2008. PMID: 17641902
Aurora A is differentially expressed in gliomas, is associated with patient survival in glioblastoma and is a potential chemotherapeutic target in gliomas.
Lehman NL, O'Donnell JP, Whiteley LJ, Stapp RT, Lehman TD, Roszka KM, Schultz LR, Williams CJ, Mikkelsen T, Brown SL, Ecsedy JA, Poisson LM. Lehman NL, et al. Among authors: lehman td. Cell Cycle. 2012 Feb 1;11(3):489-502. doi: 10.4161/cc.11.3.18996. Epub 2012 Feb 1. Cell Cycle. 2012. PMID: 22274399 Free PMC article.
Tumor-infiltrating lymphocytes in glioblastoma are associated with specific genomic alterations and related to transcriptional class.
Rutledge WC, Kong J, Gao J, Gutman DA, Cooper LA, Appin C, Park Y, Scarpace L, Mikkelsen T, Cohen ML, Aldape KD, McLendon RE, Lehman NL, Miller CR, Schniederjan MJ, Brennan CW, Saltz JH, Moreno CS, Brat DJ. Rutledge WC, et al. Among authors: lehman nl. Clin Cancer Res. 2013 Sep 15;19(18):4951-60. doi: 10.1158/1078-0432.CCR-13-0551. Epub 2013 Jul 17. Clin Cancer Res. 2013. PMID: 23864165 Free PMC article.
Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.
Cancer Genome Atlas Research Network; Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, Rheinbay E, Miller CR, Vitucci M, Morozova O, Robertson AG, Noushmehr H, Laird PW, Cherniack AD, Akbani R, Huse JT, Ciriello G, Poisson LM, Barnholtz-Sloan JS, Berger MS, Brennan C, Colen RR, Colman H, Flanders AE, Giannini C, Grifford M, Iavarone A, Jain R, Joseph I, Kim J, Kasaian K, Mikkelsen T, Murray BA, O'Neill BP, Pachter L, Parsons DW, Sougnez C, Sulman EP, Vandenberg SR, Van Meir EG, von Deimling A, Zhang H, Crain D, Lau K, Mallery D, Morris S, Paulauskis J, Penny R, Shelton T, Sherman M, Yena P, Black A, Bowen J, Dicostanzo K, Gastier-Foster J, Leraas KM, Lichtenberg TM, Pierson CR, Ramirez NC, Taylor C, Weaver S, Wise L, Zmuda E, Davidsen T, Demchok JA, Eley G, Ferguson ML, Hutter CM, Mills Shaw KR, Ozenberger BA, Sheth M, Sofia HJ, Tarnuzzer R, Wang Z, Yang L, Zenklusen JC, Ayala B, Baboud J, Chudamani S, Jensen MA, Liu J, Pihl T, Raman R, Wan Y, Wu Y, Ally A, Auman JT, Balasundaram M, Balu S, Baylin SB, Beroukhim R, Bootwalla MS, Bowlby R, Bristow CA, Brooks D, Butterfield Y, Carlsen R, Carter S, Chin L, Chu A, Chuah E, Cibulskis K, Clarke A, Coetzee SG, Dhalla N, Fenn… See abstract for full author list ➔ Cancer Genome Atlas Research Network, et al. Among authors: lehman nl. N Engl J Med. 2015 Jun 25;372(26):2481-98. doi: 10.1056/NEJMoa1402121. Epub 2015 Jun 10. N Engl J Med. 2015. PMID: 26061751 Free PMC article.
Primary Meningeal Pleomorphic Xanthoastrocytoma With Anaplastic Features: A Report of 2 Cases, One With BRAF(V600E) Mutation and Clinical Response to the BRAF Inhibitor Dabrafenib.
Usubalieva A, Pierson CR, Kavran CA, Huntoon K, Kryvenko ON, Mayer TG, Zhao W, Rock J, Ammirati M, Puduvalli VK, Lehman NL. Usubalieva A, et al. Among authors: lehman nl. J Neuropathol Exp Neurol. 2015 Oct;74(10):960-9. doi: 10.1097/NEN.0000000000000240. J Neuropathol Exp Neurol. 2015. PMID: 26352988 Free PMC article.
NHERF1/EBP50 and NF2 as diagnostic markers for choroid plexus tumors.
Georgescu MM, Mobley BC, Orr BA, Shang P, Lehman NL, Zhu X, O'Neill TJ, Rajaram V, Hatanpaa KJ, Timmons CF, Raisanen JM. Georgescu MM, et al. Among authors: lehman nl. Acta Neuropathol Commun. 2016 May 27;4(1):55. doi: 10.1186/s40478-016-0329-0. Acta Neuropathol Commun. 2016. PMID: 27229317 Free PMC article.
108 results