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ActRIIB blockade increases force-generating capacity and preserves energy supply in exercising mdx mouse muscle in vivo.
Béchir N, Pecchi E, Vilmen C, Le Fur Y, Amthor H, Bernard M, Bendahan D, Giannesini B. Béchir N, et al. Among authors: amthor h. FASEB J. 2016 Oct;30(10):3551-3562. doi: 10.1096/fj.201600271RR. Epub 2016 Jul 14. FASEB J. 2016. PMID: 27416839
These data support the clinical interest of ActRIIB blockade for reversing dystrophic muscle wasting.-Bechir, N., Pecchi, E., Vilmen, C., Le Fur, Y., Amthor, H., Bernard, M., Bendahan, D., Giannesini, B. ActRIIB blockade increases force-generating capacity and prese …
These data support the clinical interest of ActRIIB blockade for reversing dystrophic muscle wasting.-Bechir, N., Pecchi, E., Vilmen, C., Le …
Blockade of ActRIIB signaling triggers muscle fatigability and metabolic myopathy.
Relizani K, Mouisel E, Giannesini B, Hourdé C, Patel K, Morales Gonzalez S, Jülich K, Vignaud A, Piétri-Rouxel F, Fortin D, Garcia L, Blot S, Ritvos O, Bendahan D, Ferry A, Ventura-Clapier R, Schuelke M, Amthor H. Relizani K, et al. Among authors: amthor h. Mol Ther. 2014 Aug;22(8):1423-1433. doi: 10.1038/mt.2014.90. Epub 2014 May 27. Mol Ther. 2014. PMID: 24861054 Free PMC article.
Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle.
Mouisel E, Relizani K, Mille-Hamard L, Denis R, Hourdé C, Agbulut O, Patel K, Arandel L, Morales-Gonzalez S, Vignaud A, Garcia L, Ferry A, Luquet S, Billat V, Ventura-Clapier R, Schuelke M, Amthor H. Mouisel E, et al. Among authors: amthor h. Am J Physiol Regul Integr Comp Physiol. 2014 Aug 15;307(4):R444-54. doi: 10.1152/ajpregu.00377.2013. Epub 2014 Jun 25. Am J Physiol Regul Integr Comp Physiol. 2014. PMID: 24965795 Free article.
Mitochondrial impairment induced by postnatal ActRIIB blockade does not alter function and energy status in exercising mouse glycolytic muscle in vivo.
Béchir N, Pecchi É, Relizani K, Vilmen C, Le Fur Y, Bernard M, Amthor H, Bendahan D, Giannesini B. Béchir N, et al. Among authors: amthor h. Am J Physiol Endocrinol Metab. 2016 Apr 1;310(7):E539-49. doi: 10.1152/ajpendo.00370.2015. Epub 2016 Feb 2. Am J Physiol Endocrinol Metab. 2016. PMID: 26837807 Free article.
Muscle hypertrophy driven by myostatin blockade does not require stem/precursor-cell activity.
Amthor H, Otto A, Vulin A, Rochat A, Dumonceaux J, Garcia L, Mouisel E, Hourdé C, Macharia R, Friedrichs M, Relaix F, Zammit PS, Matsakas A, Patel K, Partridge T. Amthor H, et al. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7479-84. doi: 10.1073/pnas.0811129106. Epub 2009 Apr 21. Proc Natl Acad Sci U S A. 2009. PMID: 19383783 Free PMC article.
63 results