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Design, synthesis, and structure-activity relationship studies of novel 3-alkylindole derivatives as selective and highly potent myeloperoxidase inhibitors.
Soubhye J, Aldib I, Elfving B, Gelbcke M, Furtmüller PG, Podrecca M, Conotte R, Colet JM, Rousseau A, Reye F, Sarakbi A, Vanhaeverbeek M, Kauffmann JM, Obinger C, Nève J, Prévost M, Zouaoui Boudjeltia K, Dufrasne F, Van Antwerpen P. Soubhye J, et al. Among authors: furtmuller pg. J Med Chem. 2013 May 23;56(10):3943-58. doi: 10.1021/jm4001538. Epub 2013 May 6. J Med Chem. 2013. PMID: 23581551
Novel bis-arylalkylamines as myeloperoxidase inhibitors: Design, synthesis, and structure-activity relationship study.
Aldib I, Gelbcke M, Soubhye J, Prévost M, Furtmüller PG, Obinger C, Elfving B, Alard IC, Roos G, Delporte C, Berger G, Dufour D, Zouaoui Boudjeltia K, Nève J, Dufrasne F, Van Antwerpen P. Aldib I, et al. Among authors: furtmuller pg. Eur J Med Chem. 2016 Nov 10;123:746-762. doi: 10.1016/j.ejmech.2016.07.053. Epub 2016 Jul 25. Eur J Med Chem. 2016. PMID: 27537923
From Dynamic Combinatorial Chemistry to in Vivo Evaluation of Reversible and Irreversible Myeloperoxidase Inhibitors.
Soubhye J, Gelbcke M, Van Antwerpen P, Dufrasne F, Boufadi MY, Nève J, Furtmüller PG, Obinger C, Zouaoui Boudjeltia K, Meyer F. Soubhye J, et al. Among authors: furtmuller pg. ACS Med Chem Lett. 2016 Dec 2;8(2):206-210. doi: 10.1021/acsmedchemlett.6b00417. eCollection 2017 Feb 9. ACS Med Chem Lett. 2016. PMID: 28197313 Free PMC article.
Discovery of Novel Potent Reversible and Irreversible Myeloperoxidase Inhibitors Using Virtual Screening Procedure.
Soubhye J, Chikh Alard I, Aldib I, Prévost M, Gelbcke M, De Carvalho A, Furtmüller PG, Obinger C, Flemmig J, Tadrent S, Meyer F, Rousseau A, Nève J, Mathieu V, Zouaoui Boudjeltia K, Dufrasne F, Van Antwerpen P. Soubhye J, et al. Among authors: furtmuller pg. J Med Chem. 2017 Aug 10;60(15):6563-6586. doi: 10.1021/acs.jmedchem.7b00285. Epub 2017 Jul 19. J Med Chem. 2017. PMID: 28671460
Inhibition of Myeloperoxidase.
Soubhye J, Furtmüller PG, Dufrasne F, Obinger C. Soubhye J, et al. Handb Exp Pharmacol. 2021;264:261-285. doi: 10.1007/164_2020_388. Handb Exp Pharmacol. 2021. PMID: 33372235
Inactivation of human myeloperoxidase by hydrogen peroxide.
Paumann-Page M, Furtmüller PG, Hofbauer S, Paton LN, Obinger C, Kettle AJ. Paumann-Page M, et al. Arch Biochem Biophys. 2013 Nov 1;539(1):51-62. doi: 10.1016/j.abb.2013.09.004. Epub 2013 Sep 11. Arch Biochem Biophys. 2013. PMID: 24035742 Free PMC article.
177 results