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Fatty acid metabolism and the basis of brown adipose tissue function.
Calderon-Dominguez M, Mir JF, Fucho R, Weber M, Serra D, Herrero L. Calderon-Dominguez M, et al. Among authors: fucho r. Adipocyte. 2015 Dec 10;5(2):98-118. doi: 10.1080/21623945.2015.1122857. eCollection 2016 Apr-Jun. Adipocyte. 2015. PMID: 27386151 Free PMC article. Review.
Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation.
Malandrino MI, Fucho R, Weber M, Calderon-Dominguez M, Mir JF, Valcarcel L, Escoté X, Gómez-Serrano M, Peral B, Salvadó L, Fernández-Veledo S, Casals N, Vázquez-Carrera M, Villarroya F, Vendrell JJ, Serra D, Herrero L. Malandrino MI, et al. Among authors: fucho r. Am J Physiol Endocrinol Metab. 2015 May 1;308(9):E756-69. doi: 10.1152/ajpendo.00362.2014. Epub 2015 Feb 24. Am J Physiol Endocrinol Metab. 2015. PMID: 25714670 Free article.
Carnitine Palmitoyltransferase 1 Increases Lipolysis, UCP1 Protein Expression and Mitochondrial Activity in Brown Adipocytes.
Calderon-Dominguez M, Sebastián D, Fucho R, Weber M, Mir JF, García-Casarrubios E, Obregón MJ, Zorzano A, Valverde ÁM, Serra D, Herrero L. Calderon-Dominguez M, et al. Among authors: fucho r. PLoS One. 2016 Jul 20;11(7):e0159399. doi: 10.1371/journal.pone.0159399. eCollection 2016. PLoS One. 2016. PMID: 27438137 Free PMC article.
Ceramides and mitochondrial fatty acid oxidation in obesity.
Fucho R, Casals N, Serra D, Herrero L. Fucho R, et al. FASEB J. 2017 Apr;31(4):1263-1272. doi: 10.1096/fj.201601156R. Epub 2016 Dec 21. FASEB J. 2017. PMID: 28003342 Free article. Review.
In this review, we have sought to cover the importance of the ceramide species and their metabolism, the main ceramide signaling pathways in obesity, and the link between C16:0 ceramide, FAO, and obesity.-Fucho, R., Casals, N., Serra, D., Herrero, L. Ceramides and m …
In this review, we have sought to cover the importance of the ceramide species and their metabolism, the main ceramide signaling pathways in …
Liver CPT1A gene therapy reduces diet-induced hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD.
Weber M, Mera P, Casas J, Salvador J, Rodríguez A, Alonso S, Sebastián D, Soler-Vázquez MC, Montironi C, Recalde S, Fucho R, Calderón-Domínguez M, Mir JF, Bartrons R, Escola-Gil JC, Sánchez-Infantes D, Zorzano A, Llorente-Cortes V, Casals N, Valentí V, Frühbeck G, Herrero L, Serra D. Weber M, et al. Among authors: fucho r. FASEB J. 2020 Sep;34(9):11816-11837. doi: 10.1096/fj.202000678R. Epub 2020 Jul 15. FASEB J. 2020. PMID: 32666604 Free article.
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione.
Caballero F, Fernández A, Matías N, Martínez L, Fucho R, Elena M, Caballeria J, Morales A, Fernández-Checa JC, García-Ruiz C. Caballero F, et al. Among authors: fucho r. J Biol Chem. 2010 Jun 11;285(24):18528-36. doi: 10.1074/jbc.M109.099333. Epub 2010 Apr 15. J Biol Chem. 2010. PMID: 20395294 Free PMC article.
ASMase is required for chronic alcohol induced hepatic endoplasmic reticulum stress and mitochondrial cholesterol loading.
Fernandez A, Matias N, Fucho R, Ribas V, Von Montfort C, Nuño N, Baulies A, Martinez L, Tarrats N, Mari M, Colell A, Morales A, Dubuquoy L, Mathurin P, Bataller R, Caballeria J, Elena M, Balsinde J, Kaplowitz N, Garcia-Ruiz C, Fernandez-Checa JC. Fernandez A, et al. Among authors: fucho r. J Hepatol. 2013 Oct;59(4):805-13. doi: 10.1016/j.jhep.2013.05.023. Epub 2013 May 23. J Hepatol. 2013. PMID: 23707365 Free PMC article.
ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.
Fucho R, Martínez L, Baulies A, Torres S, Tarrats N, Fernandez A, Ribas V, Astudillo AM, Balsinde J, Garcia-Rovés P, Elena M, Bergheim I, Lotersztajn S, Trautwein C, Appelqvist H, Paton AW, Paton JC, Czaja MJ, Kaplowitz N, Fernandez-Checa JC, García-Ruiz C. Fucho R, et al. J Hepatol. 2014 Nov;61(5):1126-34. doi: 10.1016/j.jhep.2014.06.009. Epub 2014 Jun 16. J Hepatol. 2014. PMID: 24946279 Free PMC article.
Disrupted Mitochondrial and Metabolic Plasticity Underlie Comorbidity between Age-Related and Degenerative Disorders as Parkinson Disease and Type 2 Diabetes Mellitus.
Juárez-Flores DL, Ezquerra M, Gonzàlez-Casacuberta Ï, Ormazabal A, Morén C, Tolosa E, Fucho R, Guitart-Mampel M, Casado M, Valldeoriola F, de la Torre-Lara J, Muñoz E, Tobías E, Compta Y, García-García FJ, García-Ruiz C, Fernandez-Checa JC, Martí MJ, Grau JM, Cardellach F, Artuch R, Fernández-Santiago R, Garrabou G. Juárez-Flores DL, et al. Among authors: fucho r. Antioxidants (Basel). 2020 Oct 30;9(11):1063. doi: 10.3390/antiox9111063. Antioxidants (Basel). 2020. PMID: 33143119 Free PMC article.
22 results