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Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate.
Gomez-Lazaro M, Galindo MF, Melero-Fernandez de Mera RM, Fernandez-Gómez FJ, Concannon CG, Segura MF, Comella JX, Prehn JH, Jordan J. Gomez-Lazaro M, et al. Among authors: segura mf. Mol Pharmacol. 2007 Mar;71(3):736-43. doi: 10.1124/mol.106.030718. Epub 2006 Dec 15. Mol Pharmacol. 2007. PMID: 17172466
The long form of Fas apoptotic inhibitory molecule is expressed specifically in neurons and protects them against death receptor-triggered apoptosis.
Segura MF, Sole C, Pascual M, Moubarak RS, Perez-Garcia MJ, Gozzelino R, Iglesias V, Badiola N, Bayascas JR, Llecha N, Rodriguez-Alvarez J, Soriano E, Yuste VJ, Comella JX. Segura MF, et al. J Neurosci. 2007 Oct 17;27(42):11228-41. doi: 10.1523/JNEUROSCI.3462-07.2007. J Neurosci. 2007. PMID: 17942717 Free PMC article.
BCL-XL regulates TNF-alpha-mediated cell death independently of NF-kappaB, FLIP and IAPs.
Gozzelino R, Sole C, Llecha N, Segura MF, Moubarak RS, Iglesias-Guimarais V, Perez-Garcia MJ, Reix S, Zhang J, Badiola N, Sanchis D, Rodriguez-Alvarez J, Trullas R, Yuste VJ, Comella JX. Gozzelino R, et al. Among authors: segura mf. Cell Res. 2008 Oct;18(10):1020-36. doi: 10.1038/cr.2008.76. Cell Res. 2008. PMID: 18591962
The death receptor antagonist FLIP-L interacts with Trk and is necessary for neurite outgrowth induced by neurotrophins.
Moubarak RS, Solé C, Pascual M, Gutierrez H, Llovera M, Pérez-García MJ, Gozzelino R, Segura MF, Iglesias-Guimarais V, Reix S, Soler RM, Davies AM, Soriano E, Yuste VJ, Comella JX. Moubarak RS, et al. Among authors: segura mf. J Neurosci. 2010 Apr 28;30(17):6094-105. doi: 10.1523/JNEUROSCI.0537-10.2010. J Neurosci. 2010. PMID: 20427667 Free PMC article.
80 results