Takagahara S - Search Results

1

Development of antibody-siRNA conjugate targeted to cardiac and skeletal muscles.

Sugo T, Terada M, Oikawa T, Miyata K, Nishimura S, Kenjo E, Ogasawara-Shimizu M, Makita Y, Imaichi S, Murata S, Otake K, Kikuchi K, Teratani M, Masuda Y, Kamei T, Takagahara S, Ikeda S, Ohtaki T, Matsumoto H. Sugo T, et al. Among authors: takagahara s. J Control Release. 2016 Sep 10;237:1-13. doi: 10.1016/j.jconrel.2016.06.036. Epub 2016 Jun 29. J Control Release. 2016. PMID: 27369865

2

A Novel Selective Inhibitor of Delta-5 Desaturase Lowers Insulin Resistance and Reduces Body Weight in Diet-Induced Obese C57BL/6J Mice.

Yashiro H, Takagahara S, Tamura YO, Miyahisa I, Matsui J, Suzuki H, Ikeda S, Watanabe M. Yashiro H, et al. Among authors: takagahara s. PLoS One. 2016 Nov 10;11(11):e0166198. doi: 10.1371/journal.pone.0166198. eCollection 2016. PLoS One. 2016. PMID: 27832159 Free PMC article.

3

Effects of compound-326, a selective delta-5 desaturase inhibitor, in ApoE knockout mice with two different protocols for atherosclerosis development.

Nagase H, Takagahara S, Satomi Y, Ando A, Kubo K, Ikeda S. Nagase H, et al. Among authors: takagahara s. J Pharm Pharm Sci. 2021;24:71-83. doi: 10.18433/jpps31389. J Pharm Pharm Sci. 2021. PMID: 33600308 Free article.

4

A Novel Orally Available Delta-5 Desaturase Inhibitor Prevents Atherosclerotic Lesions Accompanied by Changes in Fatty Acid Composition and Eicosanoid Production in ApoE Knockout Mice.

Takagahara S, Shinohara H, Itokawa S, Satomi Y, Ando A, Yamamoto T, Suzuki H, Fujimoto T, Kubo K, Ikeda S. Takagahara S, et al. J Pharmacol Exp Ther. 2019 Nov;371(2):290-298. doi: 10.1124/jpet.119.259846. Epub 2019 Sep 5. J Pharmacol Exp Ther. 2019. PMID: 31488602

5

Discovery of 3,5-Diphenyl-4-methyl-1,3-oxazolidin-2-ones as Novel, Potent, and Orally Available Δ-5 Desaturase (D5D) Inhibitors.

Fujimoto J, Okamoto R, Noguchi N, Hara R, Masada S, Kawamoto T, Nagase H, Tamura YO, Imanishi M, Takagahara S, Kubo K, Tohyama K, Iida K, Andou T, Miyahisa I, Matsui J, Hayashi R, Maekawa T, Matsunaga N. Fujimoto J, et al. Among authors: takagahara s. J Med Chem. 2017 Nov 9;60(21):8963-8981. doi: 10.1021/acs.jmedchem.7b01210. Epub 2017 Oct 31. J Med Chem. 2017. PMID: 29023121

6

G alpha 12/13- and reactive oxygen species-dependent activation of c-Jun NH2-terminal kinase and p38 mitogen-activated protein kinase by angiotensin receptor stimulation in rat neonatal cardiomyocytes.

Nishida M, Tanabe S, Maruyama Y, Mangmool S, Urayama K, Nagamatsu Y, Takagahara S, Turner JH, Kozasa T, Kobayashi H, Sato Y, Kawanishi T, Inoue R, Nagao T, Kurose H. Nishida M, et al. Among authors: takagahara s. J Biol Chem. 2005 May 6;280(18):18434-41. doi: 10.1074/jbc.M409710200. Epub 2005 Mar 1. J Biol Chem. 2005. PMID: 15743761 Free article.

7

Activation mechanism of Gi and Go by reactive oxygen species.

Nishida M, Schey KL, Takagahara S, Kontani K, Katada T, Urano Y, Nagano T, Nagao T, Kurose H. Nishida M, et al. Among authors: takagahara s. J Biol Chem. 2002 Mar 15;277(11):9036-42. doi: 10.1074/jbc.M107392200. Epub 2002 Jan 7. J Biol Chem. 2002. PMID: 11781308 Free article.

8

G beta gamma counteracts G alpha(q) signaling upon alpha(1)-adrenergic receptor stimulation.

Nishida M, Takagahara S, Maruyama Y, Sugimoto Y, Nagao T, Kurose H. Nishida M, et al. Among authors: takagahara s. Biochem Biophys Res Commun. 2002 Mar 8;291(4):995-1000. doi: 10.1006/bbrc.2002.6553. Biochem Biophys Res Commun. 2002. PMID: 11866464

9

Differential requirement of G alpha12, G alpha13, G alphaq, and G beta gamma for endothelin-1-induced c-Jun NH2-terminal kinase and extracellular signal-regulated kinase activation.

Arai K, Maruyama Y, Nishida M, Tanabe S, Takagahara S, Kozasa T, Mori Y, Nagao T, Kurose H. Arai K, et al. Among authors: takagahara s. Mol Pharmacol. 2003 Mar;63(3):478-88. doi: 10.1124/mol.63.3.478. Mol Pharmacol. 2003. PMID: 12606754

10

p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors.

Sekine Y, Takagahara S, Hatanaka R, Watanabe T, Oguchi H, Noguchi T, Naguro I, Kobayashi K, Tsunoda M, Funatsu T, Nomura H, Toyoda T, Matsuki N, Kuranaga E, Miura M, Takeda K, Ichijo H. Sekine Y, et al. Among authors: takagahara s. J Cell Sci. 2011 Sep 1;124(Pt 17):3006-16. doi: 10.1242/jcs.085902. J Cell Sci. 2011. PMID: 21878507

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