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Biotransformation and bioactivation reactions - 2015 literature highlights.
Drug Metab Rev. 2016 May;48(2):113-38. doi: 10.1080/03602532.2016.1195404.
Drug Metab Rev. 2016.
PMID: 27362326
Review.
Elucidating the Mechanism of Tofacitinib Oxidative Decyanation.
Le H, Fan PW, Wong S, Ma S, Driscoll JP, Hop CE, Cyrus Khojasteh S.
Le H, et al. Among authors: cyrus khojasteh s.
Drug Metab Lett. 2016;10(2):136-43. doi: 10.2174/1872312810666160427104954.
Drug Metab Lett. 2016.
PMID: 27117606
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Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat.
Fan PW, Chen JZ, Allan Jaochico M, La H, Liu N, Mulder T, Cass RT, Durk M, Messick K, Valle N, Liu S, Lee W, Crawford JJ, Rudolf J, Murray LJ, Cyrus Khojasteh S, Wright M.
Fan PW, et al. Among authors: cyrus khojasteh s.
Drug Metab Lett. 2016;10(2):91-100. doi: 10.2174/1872312810666160411144358.
Drug Metab Lett. 2016.
PMID: 27063863
Free PMC article.
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2-Amino-[1,2,4]triazolo[1,5-a]pyridines as JAK2 inhibitors.
Siu M, Pastor R, Liu W, Barrett K, Berry M, Blair WS, Chang C, Chen JZ, Eigenbrot C, Ghilardi N, Gibbons P, He H, Hurley CA, Kenny JR, Cyrus Khojasteh S, Le H, Lee L, Lyssikatos JP, Magnuson S, Pulk R, Tsui V, Ultsch M, Xiao Y, Zhu BY, Sampath D.
Siu M, et al. Among authors: cyrus khojasteh s.
Bioorg Med Chem Lett. 2013 Sep 1;23(17):5014-21. doi: 10.1016/j.bmcl.2013.06.008. Epub 2013 Jun 15.
Bioorg Med Chem Lett. 2013.
PMID: 23870430
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