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Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.
Walerych D, Lisek K, Sommaggio R, Piazza S, Ciani Y, Dalla E, Rajkowska K, Gaweda-Walerych K, Ingallina E, Tonelli C, Morelli MJ, Amato A, Eterno V, Zambelli A, Rosato A, Amati B, Wiśniewski JR, Del Sal G. Walerych D, et al. Among authors: tonelli c. Nat Cell Biol. 2016 Aug;18(8):897-909. doi: 10.1038/ncb3380. Epub 2016 Jun 27. Nat Cell Biol. 2016. PMID: 27347849 Free article.
Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.
Sabò A, Kress TR, Pelizzola M, de Pretis S, Gorski MM, Tesi A, Morelli MJ, Bora P, Doni M, Verrecchia A, Tonelli C, Fagà G, Bianchi V, Ronchi A, Low D, Müller H, Guccione E, Campaner S, Amati B. Sabò A, et al. Among authors: tonelli c. Nature. 2014 Jul 24;511(7510):488-492. doi: 10.1038/nature13537. Epub 2014 Jul 9. Nature. 2014. PMID: 25043028 Free PMC article.
Transcriptional Regulation by Nrf2.
Tonelli C, Chio IIC, Tuveson DA. Tonelli C, et al. Antioxid Redox Signal. 2018 Dec 10;29(17):1727-1745. doi: 10.1089/ars.2017.7342. Epub 2017 Oct 20. Antioxid Redox Signal. 2018. PMID: 28899199 Free PMC article. Review.
Glutamine Anabolism Plays a Critical Role in Pancreatic Cancer by Coupling Carbon and Nitrogen Metabolism.
Bott AJ, Shen J, Tonelli C, Zhan L, Sivaram N, Jiang YP, Yu X, Bhatt V, Chiles E, Zhong H, Maimouni S, Dai W, Velasquez S, Pan JA, Muthalagu N, Morton J, Anthony TG, Feng H, Lamers WH, Murphy DJ, Guo JY, Jin J, Crawford HC, Zhang L, White E, Lin RZ, Su X, Tuveson DA, Zong WX. Bott AJ, et al. Among authors: tonelli c. Cell Rep. 2019 Oct 29;29(5):1287-1298.e6. doi: 10.1016/j.celrep.2019.09.056. Cell Rep. 2019. PMID: 31665640 Free PMC article.
SOAT1 promotes mevalonate pathway dependency in pancreatic cancer.
Oni TE, Biffi G, Baker LA, Hao Y, Tonelli C, Somerville TDD, Deschênes A, Belleau P, Hwang CI, Sánchez-Rivera FJ, Cox H, Brosnan E, Doshi A, Lumia RP, Khaledi K, Park Y, Trotman LC, Lowe SW, Krasnitz A, Vakoc CR, Tuveson DA. Oni TE, et al. Among authors: tonelli c. J Exp Med. 2020 Sep 7;217(9):e20192389. doi: 10.1084/jem.20192389. J Exp Med. 2020. PMID: 32633781 Free PMC article.
143 results