Ngwane AH - Search Results

1

Design, synthesis, and In vitro antituberculosis activity of 2(5H)-Furanone derivatives.

Ngwane AH, Panayides JL, Chouteau F, Macingwana L, Viljoen A, Baker B, Madikane E, de Kock C, Wiesner L, Chibale K, Parkinson CJ, Mmutlane EM, van Helden P, Wiid I. Ngwane AH, et al. IUBMB Life. 2016 Aug;68(8):612-20. doi: 10.1002/iub.1526. Epub 2016 Jun 27. IUBMB Life. 2016. PMID: 27346745 Free article.

2

Sulfamethoxazole enhances the antimycobacterial activity of rifampicin.

Macingwana L, Baker B, Ngwane AH, Harper C, Cotton MF, Hesseling A, Diacon AH, van Helden P, Wiid I. Macingwana L, et al. Among authors: ngwane ah. J Antimicrob Chemother. 2012 Dec;67(12):2908-11. doi: 10.1093/jac/dks306. Epub 2012 Aug 8. J Antimicrob Chemother. 2012. PMID: 22875849

3

Reversed isoniazids: Design, synthesis and evaluation against Mycobacterium tuberculosis.

Kumar M, Singh K, Ngwane AH, Hamzabegovic F, Abate G, Baker B, Wiid I, Hoft DF, Ruminski P, Chibale K. Kumar M, et al. Among authors: ngwane ah. Bioorg Med Chem. 2018 Feb 15;26(4):833-844. doi: 10.1016/j.bmc.2017.12.047. Epub 2017 Dec 29. Bioorg Med Chem. 2018. PMID: 29373270

4

The evaluation of the anti-cancer drug elesclomol that forms a redox-active copper chelate as a potential anti-tubercular drug.

Ngwane AH, Petersen RD, Baker B, Wiid I, Wong HN, Haynes RK. Ngwane AH, et al. IUBMB Life. 2019 May;71(5):532-538. doi: 10.1002/iub.2002. Epub 2019 Jan 14. IUBMB Life. 2019. PMID: 30698324 Free article.

5

Riminophenazine Derivatives as Potential Antituberculosis Agents: Synthesis, Biological, and Electrochemical Evaluations.

Bvumbi MV, van der Westhuyzen C, Mmutlane EM, Ngwane A. Bvumbi MV, et al. Molecules. 2021 Jul 10;26(14):4200. doi: 10.3390/molecules26144200. Molecules. 2021. PMID: 34299475 Free PMC article.

6

Synthesis, antimycobacterial evaluation and pharmacophore modeling of analogues of the natural product formononetin.

Mutai P, Pavadai E, Wiid I, Ngwane A, Baker B, Chibale K. Mutai P, et al. Bioorg Med Chem Lett. 2015 Jun 15;25(12):2510-3. doi: 10.1016/j.bmcl.2015.04.064. Epub 2015 Apr 28. Bioorg Med Chem Lett. 2015. PMID: 25977095

7

Proteomic analysis reveals that sulfamethoxazole induces oxidative stress in M. tuberculosis.

Sarkar R, Mdladla C, Macingwana L, Pietersen RD, Ngwane AH, Tabb DL, van Helden PD, Wiid I, Baker B. Sarkar R, et al. Among authors: ngwane ah. Tuberculosis (Edinb). 2018 Jul;111:78-85. doi: 10.1016/j.tube.2018.05.010. Epub 2018 May 17. Tuberculosis (Edinb). 2018. PMID: 30029919

8

Anti-mycobacterium tuberculosis activity of polyherbal medicines used for the treatment of tuberculosis in Eastern Cape, South Africa.

Famewo EB, Clarke AM, Wiid I, Ngwane A, van Helden P, Afolayan AJ. Famewo EB, et al. Afr Health Sci. 2017 Sep;17(3):780-789. doi: 10.4314/ahs.v17i3.21. Afr Health Sci. 2017. PMID: 29085406 Free PMC article.

9

Preliminary Evaluation of Artemisinin-Cholesterol Conjugates as Potential Drugs for the Treatment of Intractable Forms of Malaria and Tuberculosis.

Morake M, Coertzen D, Ngwane A, Wentzel JF, Wong HN, Smit FJ, Birkholtz LM, Pietersen RD, Baker B, Wiid I, N'Da DD, Haynes RK. Morake M, et al. ChemMedChem. 2018 Jan 8;13(1):67-77. doi: 10.1002/cmdc.201700579. Epub 2017 Dec 15. ChemMedChem. 2018. PMID: 29193799

10

A novel inhibitor of gyrase B is a potent drug candidate for treatment of tuberculosis and nontuberculosis mycobacterial infections.

Locher CP, Jones SM, Hanzelka BL, Perola E, Shoen CM, Cynamon MH, Ngwane AH, Wiid IJ, van Helden PD, Betoudji F, Nuermberger EL, Thomson JA. Locher CP, et al. Among authors: ngwane ah. Antimicrob Agents Chemother. 2015 Mar;59(3):1455-65. doi: 10.1128/AAC.04347-14. Epub 2014 Dec 22. Antimicrob Agents Chemother. 2015. PMID: 25534737 Free PMC article.

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