Wang L - Search Results

1

Discovery of Piperazinylquinoline Derivatives as Novel Respiratory Syncytial Virus Fusion Inhibitors.

Zheng X, Wang L, Wang B, Miao K, Xiang K, Feng S, Gao L, Shen HC, Yun H. Zheng X, et al. Among authors: wang l, wang b. ACS Med Chem Lett. 2016 Apr 20;7(6):558-62. doi: 10.1021/acsmedchemlett.5b00234. eCollection 2016 Jun 9. ACS Med Chem Lett. 2016. PMID: 27326326 Free PMC article.

2

Discovery of novel 1-phenyl-cycloalkane carbamides as potent and selective influenza fusion inhibitors.

Tang G, Qiu Z, Lin X, Li W, Zhu L, Li S, Li H, Wang L, Chen L, Wu JZ, Yang W. Tang G, et al. Among authors: wang l. Bioorg Med Chem Lett. 2010 Jun 15;20(12):3507-10. doi: 10.1016/j.bmcl.2010.04.141. Epub 2010 May 5. Bioorg Med Chem Lett. 2010. PMID: 20494579

3

Design and synthesis of benzenesulfonamide derivatives as potent anti-influenza hemagglutinin inhibitors.

Tang G, Lin X, Qiu Z, Li W, Zhu L, Wang L, Li S, Li H, Lin W, Yang M, Guo T, Chen L, Lee D, Wu JZ, Yang W. Tang G, et al. Among authors: wang l. ACS Med Chem Lett. 2011 Jun 7;2(8):603-7. doi: 10.1021/ml2000627. eCollection 2011 Aug 11. ACS Med Chem Lett. 2011. PMID: 24900355 Free PMC article.

4

Discovery of imidazopyridine derivatives as highly potent respiratory syncytial virus fusion inhibitors.

Feng S, Hong D, Wang B, Zheng X, Miao K, Wang L, Yun H, Gao L, Zhao S, Shen HC. Feng S, et al. Among authors: wang l, wang b. ACS Med Chem Lett. 2015 Jan 25;6(3):359-62. doi: 10.1021/acsmedchemlett.5b00008. eCollection 2015 Mar 12. ACS Med Chem Lett. 2015. PMID: 25941547 Free PMC article.

5

Discovery of potent and selective CDK8 inhibitors through FBDD approach.

Han X, Jiang M, Zhou C, Zhou Z, Xu Z, Wang L, Mayweg AV, Niu R, Jin TG, Yang S. Han X, et al. Among authors: wang l. Bioorg Med Chem Lett. 2017 Sep 15;27(18):4488-4492. doi: 10.1016/j.bmcl.2017.07.080. Epub 2017 Aug 1. Bioorg Med Chem Lett. 2017. PMID: 28802632

6

Discovery of Benzoazepinequinoline (BAQ) Derivatives as Novel, Potent, Orally Bioavailable Respiratory Syncytial Virus Fusion Inhibitors.

Zheng X, Liang C, Wang L, Wang B, Liu Y, Feng S, Wu JZ, Gao L, Feng L, Chen L, Guo T, Shen HC, Yun H. Zheng X, et al. Among authors: wang l, wang b. J Med Chem. 2018 Nov 21;61(22):10228-10241. doi: 10.1021/acs.jmedchem.8b01394. Epub 2018 Nov 2. J Med Chem. 2018. PMID: 30339388

7

Discovery of Ziresovir as a Potent, Selective, and Orally Bioavailable Respiratory Syncytial Virus Fusion Protein Inhibitor.

Zheng X, Gao L, Wang L, Liang C, Wang B, Liu Y, Feng S, Zhang B, Zhou M, Yu X, Xiang K, Chen L, Guo T, Shen HC, Zou G, Wu JZ, Yun H. Zheng X, et al. Among authors: wang l, wang b. J Med Chem. 2019 Jul 11;62(13):6003-6014. doi: 10.1021/acs.jmedchem.9b00654. Epub 2019 Jun 26. J Med Chem. 2019. PMID: 31194544

8

Discovery of (aza)indole derivatives as novel respiratory syncytial virus fusion inhibitors.

Zheng X, Liang C, Wang L, Miao K, Wang B, Zhang W, Chen D, Wu G, Zhu W, Guo L, Feng S, Gao L, Shen HC, Yun H. Zheng X, et al. Among authors: wang l, wang b. Medchemcomm. 2019 May 6;10(6):970-973. doi: 10.1039/c9md00178f. eCollection 2019 Jun 1. Medchemcomm. 2019. PMID: 31303995 Free PMC article.

9

Discovery of 3-Pyridyl Isoindolin-1-one Derivatives as Potent, Selective, and Orally Active Aldosterone Synthase (CYP11B2) Inhibitors.

Liu Y, Wu J, Zhou M, Chen W, Li D, Wang Z, Hornsperger B, Aebi JD, Märki HP, Kuhn B, Wang L, Kuglstatter A, Benz J, Müller S, Hochstrasser R, Ottaviani G, Xin J, Kirchner S, Mohr S, Verry P, Riboulet W, Shen HC, Mayweg AV, Amrein K, Tan X. Liu Y, et al. Among authors: wang l, wang z. J Med Chem. 2020 Jul 9;63(13):6876-6897. doi: 10.1021/acs.jmedchem.0c00233. Epub 2020 Jun 25. J Med Chem. 2020. PMID: 32530624

10

Stepwise Design of γ-Secretase Modulators with an Advanced Profile by Judicious Coordinated Structural Replacements and an Unconventional Phenyl Ring Bioisostere.

Rodríguez Sarmiento RM, Bissantz C, Bylund J, Limberg A, Neidhart W, Jakob-Roetne R, Wang L, Baumann K. Rodríguez Sarmiento RM, et al. Among authors: wang l. J Med Chem. 2020 Aug 13;63(15):8534-8553. doi: 10.1021/acs.jmedchem.0c00909. Epub 2020 Aug 4. J Med Chem. 2020. PMID: 32706964

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