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The disease-modifying effects of a Sativex-like combination of phytocannabinoids in mice with experimental autoimmune encephalomyelitis are preferentially due to Δ9-tetrahydrocannabinol acting through CB1 receptors.
Moreno-Martet M, Feliú A, Espejo-Porras F, Mecha M, Carrillo-Salinas FJ, Fernández-Ruiz J, Guaza C, de Lago E. Moreno-Martet M, et al. Mult Scler Relat Disord. 2015 Nov;4(6):505-11. doi: 10.1016/j.msard.2015.08.001. Epub 2015 Aug 5. Mult Scler Relat Disord. 2015. PMID: 26590655
A cannabigerol quinone alleviates neuroinflammation in a chronic model of multiple sclerosis.
Granja AG, Carrillo-Salinas F, Pagani A, Gómez-Cañas M, Negri R, Navarrete C, Mecha M, Mestre L, Fiebich BL, Cantarero I, Calzado MA, Bellido ML, Fernandez-Ruiz J, Appendino G, Guaza C, Muñoz E. Granja AG, et al. J Neuroimmune Pharmacol. 2012 Dec;7(4):1002-16. doi: 10.1007/s11481-012-9399-3. Epub 2012 Sep 14. J Neuroimmune Pharmacol. 2012. PMID: 22971837
41 results