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Cross-class metallo-β-lactamase inhibition by bisthiazolidines reveals multiple binding modes.
Hinchliffe P, González MM, Mojica MF, González JM, Castillo V, Saiz C, Kosmopoulou M, Tooke CL, Llarrull LI, Mahler G, Bonomo RA, Vila AJ, Spencer J. Hinchliffe P, et al. Among authors: bonomo ra. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):E3745-54. doi: 10.1073/pnas.1601368113. Epub 2016 Jun 14. Proc Natl Acad Sci U S A. 2016. PMID: 27303030 Free PMC article.
Beta-lactamases: a survey of protein diversity.
Helfand MS, Bonomo RA. Helfand MS, et al. Among authors: bonomo ra. Curr Drug Targets Infect Disord. 2003 Mar;3(1):9-23. doi: 10.2174/1568005033342181. Curr Drug Targets Infect Disord. 2003. PMID: 12570729 Review.
Inhibition of OXA-1 beta-lactamase by penems.
Bethel CR, Distler AM, Ruszczycky MW, Carey MP, Carey PR, Hujer AM, Taracila M, Helfand MS, Thomson JM, Kalp M, Anderson VE, Leonard DA, Hujer KM, Abe T, Venkatesan AM, Mansour TS, Bonomo RA. Bethel CR, et al. Among authors: bonomo ra. Antimicrob Agents Chemother. 2008 Sep;52(9):3135-43. doi: 10.1128/AAC.01677-07. Epub 2008 Jun 16. Antimicrob Agents Chemother. 2008. PMID: 18559643 Free PMC article.
Strategic design of an effective beta-lactamase inhibitor: LN-1-255, a 6-alkylidene-2'-substituted penicillin sulfone.
Pattanaik P, Bethel CR, Hujer AM, Hujer KM, Distler AM, Taracila M, Anderson VE, Fritsche TR, Jones RN, Pagadala SR, van den Akker F, Buynak JD, Bonomo RA. Pattanaik P, et al. Among authors: bonomo ra. J Biol Chem. 2009 Jan 9;284(2):945-53. doi: 10.1074/jbc.M806833200. Epub 2008 Oct 27. J Biol Chem. 2009. PMID: 18955486 Free PMC article.
726 results