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Liver-specific GH receptor gene-disrupted (LiGHRKO) mice have decreased endocrine IGF-I, increased local IGF-I, and altered body size, body composition, and adipokine profiles.
List EO, Berryman DE, Funk K, Jara A, Kelder B, Wang F, Stout MB, Zhi X, Sun L, White TA, LeBrasseur NK, Pirtskhalava T, Tchkonia T, Jensen EA, Zhang W, Masternak MM, Kirkland JL, Miller RA, Bartke A, Kopchick JJ. List EO, et al. Among authors: stout mb. Endocrinology. 2014 May;155(5):1793-805. doi: 10.1210/en.2013-2086. Epub 2014 Feb 11. Endocrinology. 2014. PMID: 24517230 Free PMC article.
TRAIL receptor deletion in mice suppresses the inflammation of nutrient excess.
Idrissova L, Malhi H, Werneburg NW, LeBrasseur NK, Bronk SF, Fingas C, Tchkonia T, Pirtskhalava T, White TA, Stout MB, Hirsova P, Krishnan A, Liedtke C, Trautwein C, Finnberg N, El-Deiry WS, Kirkland JL, Gores GJ. Idrissova L, et al. Among authors: stout mb. J Hepatol. 2015 May;62(5):1156-63. doi: 10.1016/j.jhep.2014.11.033. Epub 2014 Nov 28. J Hepatol. 2015. PMID: 25445398 Free PMC article.
Inflammation and the depot-specific secretome of human preadipocytes.
Zhu Y, Tchkonia T, Stout MB, Giorgadze N, Wang L, Li PW, Heppelmann CJ, Bouloumié A, Jensen MD, Bergen HR 3rd, Kirkland JL. Zhu Y, et al. Among authors: stout mb. Obesity (Silver Spring). 2015 May;23(5):989-99. doi: 10.1002/oby.21053. Epub 2015 Apr 10. Obesity (Silver Spring). 2015. PMID: 25864718 Free PMC article.
Growth hormone in adipose dysfunction and senescence.
Stout MB, Tchkonia T, Kirkland JL. Stout MB, et al. Oncotarget. 2015 May 10;6(13):10667-8. doi: 10.18632/oncotarget.3997. Oncotarget. 2015. PMID: 25951493 Free PMC article. No abstract available.
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age.
Xu M, Tchkonia T, Ding H, Ogrodnik M, Lubbers ER, Pirtskhalava T, White TA, Johnson KO, Stout MB, Mezera V, Giorgadze N, Jensen MD, LeBrasseur NK, Kirkland JL. Xu M, et al. Among authors: stout mb. Proc Natl Acad Sci U S A. 2015 Nov 17;112(46):E6301-10. doi: 10.1073/pnas.1515386112. Epub 2015 Nov 2. Proc Natl Acad Sci U S A. 2015. PMID: 26578790 Free PMC article.
Targeting senescent cells enhances adipogenesis and metabolic function in old age.
Xu M, Palmer AK, Ding H, Weivoda MM, Pirtskhalava T, White TA, Sepe A, Johnson KO, Stout MB, Giorgadze N, Jensen MD, LeBrasseur NK, Tchkonia T, Kirkland JL. Xu M, et al. Among authors: stout mb. Elife. 2015 Dec 19;4:e12997. doi: 10.7554/eLife.12997. Elife. 2015. PMID: 26687007 Free PMC article.
Exercise Prevents Diet-Induced Cellular Senescence in Adipose Tissue.
Schafer MJ, White TA, Evans G, Tonne JM, Verzosa GC, Stout MB, Mazula DL, Palmer AK, Baker DJ, Jensen MD, Torbenson MS, Miller JD, Ikeda Y, Tchkonia T, van Deursen JM, Kirkland JL, LeBrasseur NK. Schafer MJ, et al. Among authors: stout mb. Diabetes. 2016 Jun;65(6):1606-15. doi: 10.2337/db15-0291. Epub 2016 Mar 16. Diabetes. 2016. PMID: 26983960 Free PMC article.
85 results