Cusack S - Search Results

1

Atomic Structure and Biochemical Characterization of an RNA Endonuclease in the N Terminus of Andes Virus L Protein.

Fernández-García Y, Reguera J, Busch C, Witte G, Sánchez-Ramos O, Betzel C, Cusack S, Günther S, Reindl S. Fernández-García Y, et al. Among authors: cusack s. PLoS Pathog. 2016 Jun 14;12(6):e1005635. doi: 10.1371/journal.ppat.1005635. eCollection 2016 Jun. PLoS Pathog. 2016. PMID: 27300328 Free PMC article.

2

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.

Tarendeau F, Boudet J, Guilligay D, Mas PJ, Bougault CM, Boulo S, Baudin F, Ruigrok RW, Daigle N, Ellenberg J, Cusack S, Simorre JP, Hart DJ. Tarendeau F, et al. Among authors: cusack s. Nat Struct Mol Biol. 2007 Mar;14(3):229-33. doi: 10.1038/nsmb1212. Epub 2007 Feb 25. Nat Struct Mol Biol. 2007. PMID: 17310249

3

Host determinant residue lysine 627 lies on the surface of a discrete, folded domain of influenza virus polymerase PB2 subunit.

Tarendeau F, Crepin T, Guilligay D, Ruigrok RW, Cusack S, Hart DJ. Tarendeau F, et al. Among authors: cusack s. PLoS Pathog. 2008 Aug 29;4(8):e1000136. doi: 10.1371/journal.ppat.1000136. PLoS Pathog. 2008. PMID: 18769709 Free PMC article.

4

Bunyaviridae RNA polymerases (L-protein) have an N-terminal, influenza-like endonuclease domain, essential for viral cap-dependent transcription.

Reguera J, Weber F, Cusack S. Reguera J, et al. Among authors: cusack s. PLoS Pathog. 2010 Sep 16;6(9):e1001101. doi: 10.1371/journal.ppat.1001101. PLoS Pathog. 2010. PMID: 20862319 Free PMC article.

5

Structural analysis of specific metal chelating inhibitor binding to the endonuclease domain of influenza pH1N1 (2009) polymerase.

Kowalinski E, Zubieta C, Wolkerstorfer A, Szolar OH, Ruigrok RW, Cusack S. Kowalinski E, et al. Among authors: cusack s. PLoS Pathog. 2012;8(8):e1002831. doi: 10.1371/journal.ppat.1002831. Epub 2012 Aug 2. PLoS Pathog. 2012. PMID: 22876177 Free PMC article.

6

Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein.

Reguera J, Malet H, Weber F, Cusack S. Reguera J, et al. Among authors: cusack s. Proc Natl Acad Sci U S A. 2013 Apr 30;110(18):7246-51. doi: 10.1073/pnas.1302298110. Epub 2013 Apr 15. Proc Natl Acad Sci U S A. 2013. PMID: 23589854 Free PMC article.

7

Systems to establish bunyavirus genome replication in the absence of transcription.

Klemm C, Reguera J, Cusack S, Zielecki F, Kochs G, Weber F. Klemm C, et al. Among authors: cusack s. J Virol. 2013 Jul;87(14):8205-12. doi: 10.1128/JVI.00371-13. Epub 2013 May 22. J Virol. 2013. PMID: 23698297 Free PMC article.

For La Crosse virus (LACV; genus Orthobunyavirus), the nuclease responsible for host cell mRNA cleavage is located at the N terminus of the L protein, with an active site of five conserved amino acids (H34, D52, D79, D92, and K94) surrounding two Mn(2+) ions (J. Reguera, F. Weber …

For La Crosse virus (LACV; genus Orthobunyavirus), the nuclease responsible for host cell mRNA cleavage is located at the N terminus of the …

8

Segmented negative strand RNA virus nucleoprotein structure.

Reguera J, Cusack S, Kolakofsky D. Reguera J, et al. Among authors: cusack s. Curr Opin Virol. 2014 Apr;5:7-15. doi: 10.1016/j.coviro.2014.01.003. Epub 2014 Jan 30. Curr Opin Virol. 2014. PMID: 24486721 Review.

9

Structural Insights into Bunyavirus Replication and Its Regulation by the vRNA Promoter.

Gerlach P, Malet H, Cusack S, Reguera J. Gerlach P, et al. Among authors: cusack s. Cell. 2015 Jun 4;161(6):1267-79. doi: 10.1016/j.cell.2015.05.006. Epub 2015 May 21. Cell. 2015. PMID: 26004069 Free PMC article.

10

Crystal structure of the RNA-dependent RNA polymerase from influenza C virus.

Hengrung N, El Omari K, Serna Martin I, Vreede FT, Cusack S, Rambo RP, Vonrhein C, Bricogne G, Stuart DI, Grimes JM, Fodor E. Hengrung N, et al. Among authors: cusack s. Nature. 2015 Nov 5;527(7576):114-7. doi: 10.1038/nature15525. Epub 2015 Oct 26. Nature. 2015. PMID: 26503046 Free PMC article.

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