Gerken TA - Search Results

1

Interactions of mucins with the Tn or Sialyl Tn cancer antigens including MUC1 are due to GalNAc-GalNAc interactions.

Haugstad KE, Hadjialirezaei S, Stokke BT, Brewer CF, Gerken TA, Burchell J, Picco G, Sletmoen M. Haugstad KE, et al. Among authors: gerken ta. Glycobiology. 2016 Dec;26(12):1338-1350. doi: 10.1093/glycob/cww065. Epub 2016 Jun 9. Glycobiology. 2016. PMID: 27282157 Free PMC article.

2

Kinetic modeling confirms the biosynthesis of mucin core 1 (beta-Gal(1-3) alpha-GalNAc-O-Ser/Thr) O-glycan structures are modulated by neighboring glycosylation effects.

Gerken TA. Gerken TA. Biochemistry. 2004 Apr 13;43(14):4137-42. doi: 10.1021/bi036306a. Biochemistry. 2004. PMID: 15065856

3

Binding studies of alpha-GalNAc-specific lectins to the alpha-GalNAc (Tn-antigen) form of porcine submaxillary mucin and its smaller fragments.

Dam TK, Gerken TA, Cavada BS, Nascimento KS, Moura TR, Brewer CF. Dam TK, et al. Among authors: gerken ta. J Biol Chem. 2007 Sep 21;282(38):28256-63. doi: 10.1074/jbc.M704677200. Epub 2007 Jul 25. J Biol Chem. 2007. PMID: 17652089 Free article.

4

Conservation of peptide acceptor preferences between Drosophila and mammalian polypeptide-GalNAc transferase ortholog pairs.

Gerken TA, Ten Hagen KG, Jamison O. Gerken TA, et al. Glycobiology. 2008 Nov;18(11):861-70. doi: 10.1093/glycob/cwn073. Epub 2008 Jul 31. Glycobiology. 2008. PMID: 18669915 Free PMC article.

Previously, we reported a series of oriented random peptide substrate libraries for quantitatively determining the peptide substrate specificities of the mammalian ppGalNAc T1 and T2 (Gerken TA, Raman J, Fritz TA, Jamison O. 2006. Identification of common and …

Previously, we reported a series of oriented random peptide substrate libraries for quantitatively determining the peptide substrate specifi …

5

Systematic determination of the peptide acceptor preferences for the human UDP-Gal:glycoprotein-alpha-GalNAc beta 3 galactosyltransferase (T-synthase).

Perrine C, Ju T, Cummings RD, Gerken TA. Perrine C, et al. Among authors: gerken ta. Glycobiology. 2009 Mar;19(3):321-8. doi: 10.1093/glycob/cwn143. Epub 2008 Dec 10. Glycobiology. 2009. PMID: 19073881 Free PMC article.

6

Thermodynamics of multivalent carbohydrate-lectin cross-linking interactions: importance of entropy in the bind and jump mechanism.

Dam TK, Gerken TA, Brewer CF. Dam TK, et al. Among authors: gerken ta. Biochemistry. 2009 May 12;48(18):3822-7. doi: 10.1021/bi9002919. Biochemistry. 2009. PMID: 19292456 Free PMC article.

7

Single-molecule pair studies of the interactions of the alpha-GalNAc (Tn-antigen) form of porcine submaxillary mucin with soybean agglutinin.

Sletmoen M, Dam TK, Gerken TA, Stokke BT, Brewer CF. Sletmoen M, et al. Among authors: gerken ta. Biopolymers. 2009 Sep;91(9):719-28. doi: 10.1002/bip.21213. Biopolymers. 2009. PMID: 19384982 Free PMC article.

8

Control of mucin-type O-glycosylation: a classification of the polypeptide GalNAc-transferase gene family.

Bennett EP, Mandel U, Clausen H, Gerken TA, Fritz TA, Tabak LA. Bennett EP, et al. Among authors: gerken ta. Glycobiology. 2012 Jun;22(6):736-56. doi: 10.1093/glycob/cwr182. Epub 2011 Dec 18. Glycobiology. 2012. PMID: 22183981 Free PMC article. Review.

9

Enhanced self-association of mucins possessing the T and Tn carbohydrate cancer antigens at the single-molecule level.

Haugstad KE, Gerken TA, Stokke BT, Dam TK, Brewer CF, Sletmoen M. Haugstad KE, et al. Among authors: gerken ta. Biomacromolecules. 2012 May 14;13(5):1400-9. doi: 10.1021/bm300135h. Epub 2012 Apr 3. Biomacromolecules. 2012. PMID: 22428527 Free PMC article.

10

Probing polypeptide GalNAc-transferase isoform substrate specificities by in vitro analysis.

Kong Y, Joshi HJ, Schjoldager KT, Madsen TD, Gerken TA, Vester-Christensen MB, Wandall HH, Bennett EP, Levery SB, Vakhrushev SY, Clausen H. Kong Y, et al. Among authors: gerken ta. Glycobiology. 2015 Jan;25(1):55-65. doi: 10.1093/glycob/cwu089. Epub 2014 Aug 25. Glycobiology. 2015. PMID: 25155433 Free PMC article.

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