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Fasnall, a Selective FASN Inhibitor, Shows Potent Anti-tumor Activity in the MMTV-Neu Model of HER2(+) Breast Cancer.
Alwarawrah Y, Hughes P, Loiselle D, Carlson DA, Darr DB, Jordan JL, Xiong J, Hunter LM, Dubois LG, Thompson JW, Kulkarni MM, Ratcliff AN, Kwiek JJ, Haystead TA. Alwarawrah Y, et al. Among authors: loiselle d. Cell Chem Biol. 2016 Jun 23;23(6):678-88. doi: 10.1016/j.chembiol.2016.04.011. Epub 2016 Jun 2. Cell Chem Biol. 2016. PMID: 27265747 Free PMC article.
ROCK1 phosphorylates and activates zipper-interacting protein kinase.
Hagerty L, Weitzel DH, Chambers J, Fortner CN, Brush MH, Loiselle D, Hosoya H, Haystead TAJ. Hagerty L, et al. Among authors: loiselle d. J Biol Chem. 2007 Feb 16;282(7):4884-4893. doi: 10.1074/jbc.M609990200. Epub 2006 Dec 8. J Biol Chem. 2007. PMID: 17158456 Free article.
Human cytidine triphosphate synthetase 1 interacting proteins.
Higgins MJ, Loiselle D, Haystead TA, Graves LM. Higgins MJ, et al. Among authors: loiselle d. Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):850-7. doi: 10.1080/15257770802146502. Nucleosides Nucleotides Nucleic Acids. 2008. PMID: 18600551
Optical and radioiodinated tethered Hsp90 inhibitors reveal selective internalization of ectopic Hsp90 in malignant breast tumor cells.
Barrott JJ, Hughes PF, Osada T, Yang XY, Hartman ZC, Loiselle DR, Spector NL, Neckers L, Rajaram N, Hu F, Ramanujam N, Vaidyanathan G, Zalutsky MR, Lyerly HK, Haystead TA. Barrott JJ, et al. Chem Biol. 2013 Sep 19;20(9):1187-97. doi: 10.1016/j.chembiol.2013.08.004. Epub 2013 Sep 12. Chem Biol. 2013. PMID: 24035283 Free PMC article.
Identification of an allosteric small-molecule inhibitor selective for the inducible form of heat shock protein 70.
Howe MK, Bodoor K, Carlson DA, Hughes PF, Alwarawrah Y, Loiselle DR, Jaeger AM, Darr DB, Jordan JL, Hunter LM, Molzberger ET, Gobillot TA, Thiele DJ, Brodsky JL, Spector NL, Haystead TA. Howe MK, et al. Chem Biol. 2014 Dec 18;21(12):1648-59. doi: 10.1016/j.chembiol.2014.10.016. Epub 2014 Dec 11. Chem Biol. 2014. PMID: 25500222 Free PMC article.
161 results