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The effect of the EP3 antagonist DG-041 on male mice with diet-induced obesity.
Ceddia RP, Downey JD, Morrison RD, Kraemer MP, Davis SE, Wu J, Lindsley CW, Yin H, Daniels JS, Breyer RM. Ceddia RP, et al. Among authors: breyer rm. Prostaglandins Other Lipid Mediat. 2019 Oct;144:106353. doi: 10.1016/j.prostaglandins.2019.106353. Epub 2019 Jul 2. Prostaglandins Other Lipid Mediat. 2019. PMID: 31276827 Free PMC article.
Rat prostaglandin EP3 receptor is highly promiscuous and is the sole prostanoid receptor family member that regulates INS-1 (832/3) cell glucose-stimulated insulin secretion.
Sandhu HK, Neuman JC, Schaid MD, Davis SE, Connors KM, Challa R, Guthery E, Fenske RJ, Patibandla C, Breyer RM, Kimple ME. Sandhu HK, et al. Among authors: breyer rm. Pharmacol Res Perspect. 2021 Apr;9(2):e00736. doi: 10.1002/prp2.736. Pharmacol Res Perspect. 2021. PMID: 33694300 Free PMC article.
Inactivation of the E-prostanoid 3 receptor attenuates the angiotensin II pressor response via decreasing arterial contractility.
Chen L, Miao Y, Zhang Y, Dou D, Liu L, Tian X, Yang G, Pu D, Zhang X, Kang J, Gao Y, Wang S, Breyer MD, Wang N, Zhu Y, Huang Y, Breyer RM, Guan Y. Chen L, et al. Among authors: breyer rm, breyer md. Arterioscler Thromb Vasc Biol. 2012 Dec;32(12):3024-32. doi: 10.1161/ATVBAHA.112.254052. Epub 2012 Oct 11. Arterioscler Thromb Vasc Biol. 2012. PMID: 23065824 Free PMC article.
Prostanoid receptors: subtypes and signaling.
Breyer RM, Bagdassarian CK, Myers SA, Breyer MD. Breyer RM, et al. Among authors: breyer md. Annu Rev Pharmacol Toxicol. 2001;41:661-90. doi: 10.1146/annurev.pharmtox.41.1.661. Annu Rev Pharmacol Toxicol. 2001. PMID: 11264472 Review.
134 results