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RANKL/RANK control Brca1 mutation-.
Sigl V, Owusu-Boaitey K, Joshi PA, Kavirayani A, Wirnsberger G, Novatchkova M, Kozieradzki I, Schramek D, Edokobi N, Hersl J, Sampson A, Odai-Afotey A, Lazaro C, Gonzalez-Suarez E, Pujana MA, Cimba F, Heyn H, Vidal E, Cruickshank J, Berman H, Sarao R, Ticevic M, Uribesalgo I, Tortola L, Rao S, Tan Y, Pfeiler G, Lee EY, Bago-Horvath Z, Kenner L, Popper H, Singer C, Khokha R, Jones LP, Penninger JM. Sigl V, et al. Among authors: khokha r. Cell Res. 2016 Jul;26(7):761-74. doi: 10.1038/cr.2016.69. Epub 2016 May 31. Cell Res. 2016. PMID: 27241552 Free PMC article.
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kgamma.
Sasaki T, Irie-Sasaki J, Horie Y, Bachmaier K, Fata JE, Li M, Suzuki A, Bouchard D, Ho A, Redston M, Gallinger S, Khokha R, Mak TW, Hawkins PT, Stephens L, Scherer SW, Tsao M, Penninger JM. Sasaki T, et al. Among authors: khokha r. Nature. 2000 Aug 24;406(6798):897-902. doi: 10.1038/35022585. Nature. 2000. PMID: 10972292
Cbl-3-deficient mice exhibit normal epithelial development.
Griffiths EK, Sanchez O, Mill P, Krawczyk C, Hojilla CV, Rubin E, Nau MM, Khokha R, Lipkowitz S, Hui CC, Penninger JM. Griffiths EK, et al. Among authors: khokha r. Mol Cell Biol. 2003 Nov;23(21):7708-18. doi: 10.1128/MCB.23.21.7708-7718.2003. Mol Cell Biol. 2003. PMID: 14560016 Free PMC article.
Regulation of cancer cell migration and bone metastasis by RANKL.
Jones DH, Nakashima T, Sanchez OH, Kozieradzki I, Komarova SV, Sarosi I, Morony S, Rubin E, Sarao R, Hojilla CV, Komnenovic V, Kong YY, Schreiber M, Dixon SJ, Sims SM, Khokha R, Wada T, Penninger JM. Jones DH, et al. Among authors: khokha r. Nature. 2006 Mar 30;440(7084):692-6. doi: 10.1038/nature04524. Nature. 2006. PMID: 16572175
Progesterone induces adult mammary stem cell expansion.
Joshi PA, Jackson HW, Beristain AG, Di Grappa MA, Mote PA, Clarke CL, Stingl J, Waterhouse PD, Khokha R. Joshi PA, et al. Among authors: khokha r. Nature. 2010 Jun 10;465(7299):803-7. doi: 10.1038/nature09091. Nature. 2010. PMID: 20445538
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice.
Molyneux SD, Di Grappa MA, Beristain AG, McKee TD, Wai DH, Paderova J, Kashyap M, Hu P, Maiuri T, Narala SR, Stambolic V, Squire J, Penninger J, Sanchez O, Triche TJ, Wood GA, Kirschner LS, Khokha R. Molyneux SD, et al. Among authors: khokha r. J Clin Invest. 2010 Sep;120(9):3310-25. doi: 10.1172/JCI42391. Epub 2010 Aug 9. J Clin Invest. 2010. PMID: 20697156 Free PMC article.
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer.
Schramek D, Leibbrandt A, Sigl V, Kenner L, Pospisilik JA, Lee HJ, Hanada R, Joshi PA, Aliprantis A, Glimcher L, Pasparakis M, Khokha R, Ormandy CJ, Widschwendter M, Schett G, Penninger JM. Schramek D, et al. Among authors: khokha r. Nature. 2010 Nov 4;468(7320):98-102. doi: 10.1038/nature09387. Epub 2010 Sep 29. Nature. 2010. PMID: 20881962 Free PMC article.
176 results