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A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Nat Med. 2016 Jul;22(7):744-53. doi: 10.1038/nm.4107. Epub 2016 May 23.
Nat Med. 2016.
PMID: 27213815
In vivo RNAi screening identifies a mechanism of sorafenib resistance in liver cancer.
Rudalska R, Dauch D, Longerich T, McJunkin K, Wuestefeld T, Kang TW, Hohmeyer A, Pesic M, Leibold J, von Thun A, Schirmacher P, Zuber J, Weiss KH, Powers S, Malek NP, Eilers M, Sipos B, Lowe SW, Geffers R, Laufer S, Zender L.
Rudalska R, et al. Among authors: hohmeyer a.
Nat Med. 2014 Oct;20(10):1138-46. doi: 10.1038/nm.3679. Epub 2014 Sep 14.
Nat Med. 2014.
PMID: 25216638
Free PMC article.
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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development.
Kang TW, Yevsa T, Woller N, Hoenicke L, Wuestefeld T, Dauch D, Hohmeyer A, Gereke M, Rudalska R, Potapova A, Iken M, Vucur M, Weiss S, Heikenwalder M, Khan S, Gil J, Bruder D, Manns M, Schirmacher P, Tacke F, Ott M, Luedde T, Longerich T, Kubicka S, Zender L.
Kang TW, et al. Among authors: hohmeyer a.
Nature. 2011 Nov 9;479(7374):547-51. doi: 10.1038/nature10599.
Nature. 2011.
PMID: 22080947
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A Direct in vivo RNAi screen identifies MKK4 as a key regulator of liver regeneration.
Wuestefeld T, Pesic M, Rudalska R, Dauch D, Longerich T, Kang TW, Yevsa T, Heinzmann F, Hoenicke L, Hohmeyer A, Potapova A, Rittelmeier I, Jarek M, Geffers R, Scharfe M, Klawonn F, Schirmacher P, Malek NP, Ott M, Nordheim A, Vogel A, Manns MP, Zender L.
Wuestefeld T, et al. Among authors: hohmeyer a.
Cell. 2013 Apr 11;153(2):389-401. doi: 10.1016/j.cell.2013.03.026.
Cell. 2013.
PMID: 23582328
Free article.
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Adaptive immunity suppresses formation and progression of diethylnitrosamine-induced liver cancer.
Schneider C, Teufel A, Yevsa T, Staib F, Hohmeyer A, Walenda G, Zimmermann HW, Vucur M, Huss S, Gassler N, Wasmuth HE, Lira SA, Zender L, Luedde T, Trautwein C, Tacke F.
Schneider C, et al. Among authors: hohmeyer a.
Gut. 2012 Dec;61(12):1733-43. doi: 10.1136/gutjnl-2011-301116. Epub 2012 Jan 20.
Gut. 2012.
PMID: 22267597
Free PMC article.
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SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer.
Tordella L, Khan S, Hohmeyer A, Banito A, Klotz S, Raguz S, Martin N, Dhamarlingam G, Carroll T, González Meljem JM, Deswal S, Martínez-Barbera JP, García-Escudero R, Zuber J, Zender L, Gil J.
Tordella L, et al. Among authors: hohmeyer a.
Genes Dev. 2016 Oct 1;30(19):2187-2198. doi: 10.1101/gad.286112.116. Epub 2016 Oct 13.
Genes Dev. 2016.
PMID: 27737960
Free PMC article.
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