Hughes TR - Search Results

1

Complement system activation contributes to the ependymal damage induced by microbial neuraminidase.

Granados-Durán P, López-Ávalos MD, Hughes TR, Johnson K, Morgan BP, Tamburini PP, Fernández-Llebrez P, Grondona JM. Granados-Durán P, et al. Among authors: hughes tr. J Neuroinflammation. 2016 May 21;13(1):115. doi: 10.1186/s12974-016-0576-9. J Neuroinflammation. 2016. PMID: 27209022 Free PMC article.

2

Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement.

Hughes TR, Piddlesden SJ, Williams JD, Harrison RA, Morgan BP. Hughes TR, et al. Biochem J. 1992 May 15;284 ( Pt 1)(Pt 1):169-76. doi: 10.1042/bj2840169. Biochem J. 1992. PMID: 1376109 Free PMC article.

3

Immunolocalization and characterization of the rat analogue of human CD59 in kidney and glomerular cells.

Hughes TR, Meri S, Davies M, Williams JD, Morgan BP. Hughes TR, et al. Immunology. 1993 Nov;80(3):439-44. Immunology. 1993. PMID: 7507093 Free PMC article.

4

Complement regulator loss on apoptotic neuronal cells causes increased complement activation and promotes both phagocytosis and cell lysis.

Cole DS, Hughes TR, Gasque P, Morgan BP. Cole DS, et al. Among authors: hughes tr. Mol Immunol. 2006 May;43(12):1953-64. doi: 10.1016/j.molimm.2005.11.015. Epub 2006 Jan 10. Mol Immunol. 2006. PMID: 16406094

5

p53 regulates cellular resistance to complement lysis through enhanced expression of CD59.

Donev RM, Cole DS, Sivasankar B, Hughes TR, Morgan BP. Donev RM, et al. Among authors: hughes tr. Cancer Res. 2006 Feb 15;66(4):2451-8. doi: 10.1158/0008-5472.CAN-05-3191. Cancer Res. 2006. PMID: 16489052 Free article. Retracted.

6

CD59a deficient mice display reduced B cell activity and antibody production in response to T-dependent antigens.

Sivasankar B, Donev RM, Longhi MP, Hughes TR, Davies R, Cole DS, Morgan BP, Marchbank KJ. Sivasankar B, et al. Among authors: hughes tr. Mol Immunol. 2007 Apr;44(11):2978-87. doi: 10.1016/j.molimm.2006.12.025. Epub 2007 Feb 12. Mol Immunol. 2007. PMID: 17296227

7

High-resolution structures of bacterially expressed soluble human CD59.

Leath KJ, Johnson S, Roversi P, Hughes TR, Smith RA, Mackenzie L, Morgan BP, Lea SM. Leath KJ, et al. Among authors: hughes tr. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Aug 1;63(Pt 8):648-52. doi: 10.1107/S1744309107033477. Epub 2007 Jul 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007. PMID: 17671359 Free PMC article.

8

Modulation of CD59 expression by restrictive silencer factor-derived peptides in cancer immunotherapy for neuroblastoma.

Donev RM, Gray LC, Sivasankar B, Hughes TR, van den Berg CW, Morgan BP. Donev RM, et al. Among authors: hughes tr. Cancer Res. 2008 Jul 15;68(14):5979-87. doi: 10.1158/0008-5472.CAN-07-6828. Cancer Res. 2008. PMID: 18632654 Free PMC article. Retracted.

9

Crry deficiency in complement sufficient mice: C3 consumption occurs without associated renal injury.

Ruseva MM, Hughes TR, Donev RM, Sivasankar B, Pickering MC, Wu X, Harris CL, Morgan BP. Ruseva MM, et al. Among authors: hughes tr. Mol Immunol. 2009 Feb;46(5):803-11. doi: 10.1016/j.molimm.2008.09.003. Epub 2008 Oct 22. Mol Immunol. 2009. PMID: 18947875

10

Identification of the high affinity binding site in the Streptococcus intermedius toxin intermedilysin for its membrane receptor, the human complement regulator CD59.

Hughes TR, Ross KS, Cowan GJ, Sivasankar B, Harris CL, Mitchell TJ, Morgan BP. Hughes TR, et al. Mol Immunol. 2009 Apr;46(7):1561-7. doi: 10.1016/j.molimm.2009.01.003. Epub 2009 Feb 6. Mol Immunol. 2009. PMID: 19200600 Free PMC article.

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