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Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability.
Nucl Med Biol. 2016 Jul;43(7):424-37. doi: 10.1016/j.nucmedbio.2016.03.005. Epub 2016 Mar 17.
Nucl Med Biol. 2016.
PMID: 27179748
Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation.
Hugenberg V, Riemann B, Hermann S, Schober O, Schäfers M, Szardenings K, Lebedev A, Gangadharmath U, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S.
Hugenberg V, et al. Among authors: szardenings k.
J Med Chem. 2013 Sep 12;56(17):6858-70. doi: 10.1021/jm4006753. Epub 2013 Aug 16.
J Med Chem. 2013.
PMID: 23899323
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Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid.
Hugenberg V, Behrends M, Wagner S, Hermann S, Schäfers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G.
Hugenberg V, et al. Among authors: szardenings k.
EJNMMI Radiopharm Chem. 2018 Jul 27;3:10. doi: 10.1186/s41181-018-0045-0. eCollection 2018 Dec.
EJNMMI Radiopharm Chem. 2018.
PMID: 30101186
Free PMC article.
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Atherosclerotic plaque uptake of a novel integrin tracer ¹⁸F-Flotegatide in a mouse model of atherosclerosis.
Su H, Gorodny N, Gomez LF, Gangadharmath UB, Mu F, Chen G, Walsh JC, Szardenings K, Berman DS, Kolb HC, Tamarappoo BK.
Su H, et al. Among authors: szardenings k.
J Nucl Cardiol. 2014 Jun;21(3):553-62. doi: 10.1007/s12350-014-9879-3. Epub 2014 Mar 14.
J Nucl Cardiol. 2014.
PMID: 24627345
Free PMC article.
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Noninvasive molecular imaging of apoptosis in a mouse model of anthracycline-induced cardiotoxicity.
Su H, Gorodny N, Gomez LF, Gangadharmath U, Mu F, Chen G, Walsh JC, Szardenings K, Kolb HC, Tamarappoo B.
Su H, et al. Among authors: szardenings k.
Circ Cardiovasc Imaging. 2015 Feb;8(2):e001952. doi: 10.1161/CIRCIMAGING.114.001952.
Circ Cardiovasc Imaging. 2015.
PMID: 25657296
Free PMC article.
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Repeatability of hypoxia PET imaging using [¹⁸F]HX4 in lung and head and neck cancer patients: a prospective multicenter trial.
Zegers CM, van Elmpt W, Szardenings K, Kolb H, Waxman A, Subramaniam RM, Moon DH, Brunetti JC, Srinivas SM, Lambin P, Chien D.
Zegers CM, et al. Among authors: szardenings k.
Eur J Nucl Med Mol Imaging. 2015 Nov;42(12):1840-9. doi: 10.1007/s00259-015-3100-z. Epub 2015 Jul 2.
Eur J Nucl Med Mol Imaging. 2015.
PMID: 26136164
Free PMC article.
Clinical Trial.
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Fishing for targets: novel approaches using small molecule baits.
Szardenings K, Li B, Ma L, Wu M.
Szardenings K, et al.
Drug Discov Today Technol. 2004 Sep;1(1):9-15. doi: 10.1016/j.ddtec.2004.08.009.
Drug Discov Today Technol. 2004.
PMID: 24981262
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