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Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability.
Hugenberg V, Hermann S, Galla F, Schäfers M, Wünsch B, Kolb HC, Szardenings K, Lebedev A, Walsh JC, Mocharla VP, Gangadharmath UB, Kopka K, Wagner S. Hugenberg V, et al. Among authors: szardenings k. Nucl Med Biol. 2016 Jul;43(7):424-37. doi: 10.1016/j.nucmedbio.2016.03.005. Epub 2016 Mar 17. Nucl Med Biol. 2016. PMID: 27179748
Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation.
Hugenberg V, Riemann B, Hermann S, Schober O, Schäfers M, Szardenings K, Lebedev A, Gangadharmath U, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. Hugenberg V, et al. Among authors: szardenings k. J Med Chem. 2013 Sep 12;56(17):6858-70. doi: 10.1021/jm4006753. Epub 2013 Aug 16. J Med Chem. 2013. PMID: 23899323
Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid.
Hugenberg V, Behrends M, Wagner S, Hermann S, Schäfers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G. Hugenberg V, et al. Among authors: szardenings k. EJNMMI Radiopharm Chem. 2018 Jul 27;3:10. doi: 10.1186/s41181-018-0045-0. eCollection 2018 Dec. EJNMMI Radiopharm Chem. 2018. PMID: 30101186 Free PMC article.
Repeatability of hypoxia PET imaging using [¹⁸F]HX4 in lung and head and neck cancer patients: a prospective multicenter trial.
Zegers CM, van Elmpt W, Szardenings K, Kolb H, Waxman A, Subramaniam RM, Moon DH, Brunetti JC, Srinivas SM, Lambin P, Chien D. Zegers CM, et al. Among authors: szardenings k. Eur J Nucl Med Mol Imaging. 2015 Nov;42(12):1840-9. doi: 10.1007/s00259-015-3100-z. Epub 2015 Jul 2. Eur J Nucl Med Mol Imaging. 2015. PMID: 26136164 Free PMC article. Clinical Trial.