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The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation.
Uziel T, Zindy F, Xie S, Lee Y, Forget A, Magdaleno S, Rehg JE, Calabrese C, Solecki D, Eberhart CG, Sherr SE, Plimmer S, Clifford SC, Hatten ME, McKinnon PJ, Gilbertson RJ, Curran T, Sherr CJ, Roussel MF. Uziel T, et al. Among authors: roussel mf. Genes Dev. 2005 Nov 15;19(22):2656-67. doi: 10.1101/gad.1368605. Epub 2005 Oct 31. Genes Dev. 2005. PMID: 16260494 Free PMC article.
Subtypes of medulloblastoma have distinct developmental origins.
Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ. Gibson P, et al. Among authors: roussel mf. Nature. 2010 Dec 23;468(7327):1095-9. doi: 10.1038/nature09587. Epub 2010 Dec 8. Nature. 2010. PMID: 21150899 Free PMC article.
Medulloblastoma: advances and challenges.
Roussel MF, Robinson G. Roussel MF, et al. F1000 Biol Rep. 2011;3:5. doi: 10.3410/B3-5. Epub 2011 Mar 1. F1000 Biol Rep. 2011. PMID: 21655335 Free PMC article.
A mouse model of the most aggressive subgroup of human medulloblastoma.
Kawauchi D, Robinson G, Uziel T, Gibson P, Rehg J, Gao C, Finkelstein D, Qu C, Pounds S, Ellison DW, Gilbertson RJ, Roussel MF. Kawauchi D, et al. Among authors: roussel mf. Cancer Cell. 2012 Feb 14;21(2):168-80. doi: 10.1016/j.ccr.2011.12.023. Cancer Cell. 2012. PMID: 22340591 Free PMC article.
Novel mutations target distinct subgroups of medulloblastoma.
Robinson G, Parker M, Kranenburg TA, Lu C, Chen X, Ding L, Phoenix TN, Hedlund E, Wei L, Zhu X, Chalhoub N, Baker SJ, Huether R, Kriwacki R, Curley N, Thiruvenkatam R, Wang J, Wu G, Rusch M, Hong X, Becksfort J, Gupta P, Ma J, Easton J, Vadodaria B, Onar-Thomas A, Lin T, Li S, Pounds S, Paugh S, Zhao D, Kawauchi D, Roussel MF, Finkelstein D, Ellison DW, Lau CC, Bouffet E, Hassall T, Gururangan S, Cohn R, Fulton RS, Fulton LL, Dooling DJ, Ochoa K, Gajjar A, Mardis ER, Wilson RK, Downing JR, Zhang J, Gilbertson RJ. Robinson G, et al. Among authors: roussel mf. Nature. 2012 Aug 2;488(7409):43-8. doi: 10.1038/nature11213. Nature. 2012. PMID: 22722829 Free PMC article.
Role of MYC in Medulloblastoma.
Roussel MF, Robinson GW. Roussel MF, et al. Cold Spring Harb Perspect Med. 2013 Nov 1;3(11):a014308. doi: 10.1101/cshperspect.a014308. Cold Spring Harb Perspect Med. 2013. PMID: 24186490 Free PMC article. Review.
Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.
Morfouace M, Shelat A, Jacus M, Freeman BB 3rd, Turner D, Robinson S, Zindy F, Wang YD, Finkelstein D, Ayrault O, Bihannic L, Puget S, Li XN, Olson JM, Robinson GW, Guy RK, Stewart CF, Gajjar A, Roussel MF. Morfouace M, et al. Among authors: roussel mf. Cancer Cell. 2014 Apr 14;25(4):516-29. doi: 10.1016/j.ccr.2014.02.009. Epub 2014 Mar 27. Cancer Cell. 2014. PMID: 24684846 Free PMC article.
285 results