Phillips WA - Search Results

1

Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution.

Denoyer D, Pearson HB, Clatworthy SA, Smith ZM, Francis PS, Llanos RM, Volitakis I, Phillips WA, Meggyesy PM, Masaldan S, Cater MA. Denoyer D, et al. Among authors: phillips wa. Oncotarget. 2016 Jun 14;7(24):37064-37080. doi: 10.18632/oncotarget.9245. Oncotarget. 2016. PMID: 27175597 Free PMC article.

2

The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis.

Pearson HB, McGlinn E, Phesse TJ, Schlüter H, Srikumar A, Gödde NJ, Woelwer CB, Ryan A, Phillips WA, Ernst M, Kaur P, Humbert P. Pearson HB, et al. Among authors: phillips wa. Mol Cancer. 2015 Sep 17;14:169. doi: 10.1186/s12943-015-0440-z. Mol Cancer. 2015. PMID: 26376988 Free PMC article.

3

Novel metastatic models of esophageal adenocarcinoma derived from FLO-1 cells highlight the importance of E-cadherin in cancer metastasis.

Liu DS, Hoefnagel SJ, Fisher OM, Krishnadath KK, Montgomery KG, Busuttil RA, Colebatch AJ, Read M, Duong CP, Phillips WA, Clemons NJ. Liu DS, et al. Among authors: phillips wa. Oncotarget. 2016 Dec 13;7(50):83342-83358. doi: 10.18632/oncotarget.13391. Oncotarget. 2016. PMID: 27863424 Free PMC article.

4

Inhibiting the system x_C^-/glutathione axis selectively targets cancers with mutant-p53 accumulation.

Liu DS, Duong CP, Haupt S, Montgomery KG, House CM, Azar WJ, Pearson HB, Fisher OM, Read M, Guerra GR, Haupt Y, Cullinane C, Wiman KG, Abrahmsen L, Phillips WA, Clemons NJ. Liu DS, et al. Among authors: phillips wa. Nat Commun. 2017 Mar 28;8:14844. doi: 10.1038/ncomms14844. Nat Commun. 2017. PMID: 28348409 Free PMC article.

5

Combined MEK and Pi3'-kinase inhibition reveals synergy in targeting thyroid cancer in vitro and in vivo.

ElMokh O, Ruffieux-Daidié D, Roelli MA, Stooss A, Phillips WA, Gertsch J, Dettmer MS, Charles RP. ElMokh O, et al. Among authors: phillips wa. Oncotarget. 2017 Apr 11;8(15):24604-24620. doi: 10.18632/oncotarget.15599. Oncotarget. 2017. PMID: 28445948 Free PMC article.

6

Identification of Pik3ca Mutation as a Genetic Driver of Prostate Cancer That Cooperates with Pten Loss to Accelerate Progression and Castration-Resistant Growth.

Pearson HB, Li J, Meniel VS, Fennell CM, Waring P, Montgomery KG, Rebello RJ, Macpherson AA, Koushyar S, Furic L, Cullinane C, Clarkson RW, Smalley MJ, Simpson KJ, Phesse TJ, Shepherd PR, Humbert PO, Sansom OJ, Phillips WA. Pearson HB, et al. Among authors: phillips wa. Cancer Discov. 2018 Jun;8(6):764-779. doi: 10.1158/2159-8290.CD-17-0867. Epub 2018 Mar 26. Cancer Discov. 2018. PMID: 29581176 Free article.

7

PLEKHS1 drives PI3Ks and remodels pathway homeostasis in PTEN-null prostate.

Chessa TAM, Jung P, Anwar A, Suire S, Anderson KE, Barneda D, Kielkowska A, Sadiq BA, Lai IW, Felisbino S, Turnham DJ, Pearson HB, Phillips WA, Sasaki J, Sasaki T, Oxley D, Spensberger D, Segonds-Pichon A, Wilson M, Walker S, Okkenhaug H, Cosulich S, Hawkins PT, Stephens LR. Chessa TAM, et al. Among authors: phillips wa. Mol Cell. 2023 Aug 17;83(16):2991-3009.e13. doi: 10.1016/j.molcel.2023.07.015. Epub 2023 Aug 10. Mol Cell. 2023. PMID: 37567175 Free article.

8

Preclinical models of esophageal adenocarcinoma for drug development.

Liu DS, Duong CP, Phillips WA, Clemons NJ. Liu DS, et al. Among authors: phillips wa. Discov Med. 2016 Dec;22(123):371-379. Discov Med. 2016. PMID: 28147219 Free article. Review.

9

PIK3CA^H1047R-induced paradoxical ERK activation results in resistance to BRAF^V600E specific inhibitors in BRAF^V600E PIK3CA^H1047R double mutant thyroid tumors.

Roelli MA, Ruffieux-Daidié D, Stooss A, ElMokh O, Phillips WA, Dettmer MS, Charles RP. Roelli MA, et al. Among authors: phillips wa. Oncotarget. 2017 Oct 11;8(61):103207-103222. doi: 10.18632/oncotarget.21732. eCollection 2017 Nov 28. Oncotarget. 2017. PMID: 29262556 Free PMC article.

10

Pretreatment transcriptional profiling for predicting response to neoadjuvant chemoradiotherapy in rectal adenocarcinoma.

Brettingham-Moore KH, Duong CP, Greenawalt DM, Heriot AG, Ellul J, Dow CA, Murray WK, Hicks RJ, Tjandra J, Chao M, Bui A, Joon DL, Thomas RJ, Phillips WA. Brettingham-Moore KH, et al. Among authors: phillips wa. Clin Cancer Res. 2011 May 1;17(9):3039-47. doi: 10.1158/1078-0432.CCR-10-2915. Epub 2011 Jan 11. Clin Cancer Res. 2011. PMID: 21224373

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