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Acidic tumor microenvironment abrogates the efficacy of mTORC1 inhibitors.
Faes S, Duval AP, Planche A, Uldry E, Santoro T, Pythoud C, Stehle JC, Horlbeck J, Letovanec I, Riggi N, Demartines N, Dormond O. Faes S, et al. Among authors: pythoud c. Mol Cancer. 2016 Dec 5;15(1):78. doi: 10.1186/s12943-016-0562-y. Mol Cancer. 2016. PMID: 27919264 Free PMC article.
Therapeutic efficacy of regulable GDNF expression for Huntington's and Parkinson's disease by a high-induction, background-free "GeneSwitch" vector.
Cheng S, Tereshchenko J, Zimmer V, Vachey G, Pythoud C, Rey M, Liefhebber J, Raina A, Streit F, Mazur A, Bähr M, Konstantinova P, Déglon N, Kügler S. Cheng S, et al. Among authors: pythoud c. Exp Neurol. 2018 Nov;309:79-90. doi: 10.1016/j.expneurol.2018.07.017. Epub 2018 Aug 1. Exp Neurol. 2018. PMID: 30076831
Humoral Responses Against Variants of Concern by COVID-19 mRNA Vaccines in Immunocompromised Patients.
Obeid M, Suffiotti M, Pellaton C, Bouchaab H, Cairoli A, Salvadé V, Stevenel C, Hottinger R, Pythoud C, Coutechier L, Molinari L, Trono D, Ribi C, Gottardo R, Fenwick C, Pascual M, Duchosal MA, Peters S, Pantaleo G. Obeid M, et al. Among authors: pythoud c. JAMA Oncol. 2022 May 1;8(5):e220446. doi: 10.1001/jamaoncol.2022.0446. Epub 2022 May 19. JAMA Oncol. 2022. PMID: 35271706 Free PMC article.
PAR2 promotes vaccine-induced protection against Helicobacter infection in mice.
Velin D, Narayan S, Bernasconi E, Busso N, Ramelli G, Maillard MH, Bachmann D, Pythoud C, Bouzourene H, Michetti P, So A. Velin D, et al. Among authors: pythoud c. Gastroenterology. 2011 Oct;141(4):1273-82, 1282.e1. doi: 10.1053/j.gastro.2011.06.038. Epub 2011 Jun 23. Gastroenterology. 2011. PMID: 21703999
AAV5-miHTT gene therapy demonstrates suppression of mutant huntingtin aggregation and neuronal dysfunction in a rat model of Huntington's disease.
Miniarikova J, Zimmer V, Martier R, Brouwers CC, Pythoud C, Richetin K, Rey M, Lubelski J, Evers MM, van Deventer SJ, Petry H, Déglon N, Konstantinova P. Miniarikova J, et al. Among authors: pythoud c. Gene Ther. 2017 Oct;24(10):630-639. doi: 10.1038/gt.2017.71. Epub 2017 Aug 3. Gene Ther. 2017. PMID: 28771234 Free PMC article.
26 results