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Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-κB-dependent manner.
Fitzpatrick SF, Fábián Z, Schaible B, Lenihan CR, Schwarzl T, Rodriguez J, Zheng X, Li Z, Tambuwala MM, Higgins DG, O'Meara Y, Slattery C, Manresa MC, Fraisl P, Bruning U, Baes M, Carmeliet P, Doherty G, von Kriegsheim A, Cummins EP, Taylor CT. Fitzpatrick SF, et al. Among authors: tambuwala mm. Biochem Biophys Res Commun. 2016 Jun 3;474(3):579-586. doi: 10.1016/j.bbrc.2016.04.085. Epub 2016 Apr 27. Biochem Biophys Res Commun. 2016. PMID: 27130823 Free article.
PGC-1alpha is coupled to HIF-1alpha-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells.
O'Hagan KA, Cocchiglia S, Zhdanov AV, Tambuwala MM, Cummins EP, Monfared M, Agbor TA, Garvey JF, Papkovsky DB, Taylor CT, Allan BB. O'Hagan KA, et al. Among authors: tambuwala mm. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2188-93. doi: 10.1073/pnas.0808801106. Epub 2009 Jan 28. Proc Natl Acad Sci U S A. 2009. PMID: 19179292 Free PMC article.
Loss of prolyl hydroxylase-1 protects against colitis through reduced epithelial cell apoptosis and increased barrier function.
Tambuwala MM, Cummins EP, Lenihan CR, Kiss J, Stauch M, Scholz CC, Fraisl P, Lasitschka F, Mollenhauer M, Saunders SP, Maxwell PH, Carmeliet P, Fallon PG, Schneider M, Taylor CT. Tambuwala MM, et al. Gastroenterology. 2010 Dec;139(6):2093-101. doi: 10.1053/j.gastro.2010.06.068. Epub 2010 Jun 30. Gastroenterology. 2010. PMID: 20600011
A dynamic model of the hypoxia-inducible factor 1α (HIF-1α) network.
Nguyen LK, Cavadas MA, Scholz CC, Fitzpatrick SF, Bruning U, Cummins EP, Tambuwala MM, Manresa MC, Kholodenko BN, Taylor CT, Cheong A. Nguyen LK, et al. Among authors: tambuwala mm. J Cell Sci. 2013 Mar 15;126(Pt 6):1454-63. doi: 10.1242/jcs.119974. Epub 2013 Feb 6. J Cell Sci. 2013. PMID: 23390316
Regulation of IL-1β-induced NF-κB by hydroxylases links key hypoxic and inflammatory signaling pathways.
Scholz CC, Cavadas MA, Tambuwala MM, Hams E, Rodríguez J, von Kriegsheim A, Cotter P, Bruning U, Fallon PG, Cheong A, Cummins EP, Taylor CT. Scholz CC, et al. Among authors: tambuwala mm. Proc Natl Acad Sci U S A. 2013 Nov 12;110(46):18490-5. doi: 10.1073/pnas.1309718110. Epub 2013 Oct 21. Proc Natl Acad Sci U S A. 2013. PMID: 24145445 Free PMC article.
A dynamic model of the hypoxia-inducible factor 1a (HIF-1a) network.
Nguyen LK, Cavadas MA, Scholz CC, Fitzpatrick SF, Bruning U, Cummins EP, Tambuwala MM, Manresa MC, Kholodenko BN, Taylor CT, Cheong A. Nguyen LK, et al. Among authors: tambuwala mm. J Cell Sci. 2015 Jan 15;128(2):422. doi: 10.1242/jcs.167304. J Cell Sci. 2015. PMID: 25589793 No abstract available.
REST is a hypoxia-responsive transcriptional repressor.
Cavadas MA, Mesnieres M, Crifo B, Manresa MC, Selfridge AC, Keogh CE, Fabian Z, Scholz CC, Nolan KA, Rocha LM, Tambuwala MM, Brown S, Wdowicz A, Corbett D, Murphy KJ, Godson C, Cummins EP, Taylor CT, Cheong A. Cavadas MA, et al. Among authors: tambuwala mm. Sci Rep. 2016 Aug 17;6:31355. doi: 10.1038/srep31355. Sci Rep. 2016. PMID: 27531581 Free PMC article.
242 results